News tagged with enzyme inhibitors

Mapping of protein inhibitors facilitates development of tailor-made anticancer agents

(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...

Biology / Biotechnology

created Feb 20, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Four new leads identified for anti-cancer drugs

Four new anti-cancer drug leads have been identified in a research paper published online this week in Bioorganic and Medicinal Chemistry.

Chemistry / Biochemistry

created Nov 28, 2011 | popularity not rated yet | comments 1

First-of-its-kind study creates new tool for targeted cancer drug development

In a technical tour de force, scientists at Fox Chase Cancer Center have cataloged and cross-indexed the actions of 178 candidate drugs capable of blocking the activity of one or more of 300 enzymes, including enzymes critical ...

Biology / Biotechnology

created Oct 30, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists create natural Alzheimer's-fighting compound in lab

Scientists at Yale University have developed the first practical method to create a compound called huperzine A in the lab. The compound, which occurs naturally in a species of moss found in China, is an enzyme inhibitor ...

Chemistry / Biochemistry

created Aug 25, 2011 | popularity 5 / 5 (2) | comments 3 | with audio podcast

New class of compounds offers great potential for research and drug development

Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.

Chemistry / Biochemistry

created May 15, 2011 | popularity 4.5 / 5 (4) | comments 1 | with audio podcast

New direction for epilepsy treatment

If common anticonvulsant drugs fail to manage epileptic seizures, then perhaps the anti-inflammatory route is the way to go. That's according to Mattia Maroso and colleagues from the Mario Negri Institute for Pharmacological ...

Medicine & Health / Neuroscience

created Mar 28, 2011 | popularity not rated yet | comments 0

Fluorescent compounds make tumors glow

A series of novel imaging agents could light up tumors as they begin to form - before they turn deadly - and signal their transition to aggressive cancers.

Medicine & Health / Cancer

created Apr 29, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Enzyme is key to clogged arteries

Scientists at Queen Mary, University of London have made an important discovery in understanding what causes arteries to clog up.

Medicine & Health / Medical research

created Sep 24, 2009 | popularity 5 / 5 (1) | comments 0

New microchip technology performs 1,000 chemical reactions at once

(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer ...

Chemistry / Analytical Chemistry

created Aug 03, 2009 | popularity 5 / 5 (11) | comments 3

Magic ingredient in breast milk protects babies' intestines

Scientists at Queen Mary, University of London have discovered that an ingredient in human breast milk protects and repairs the delicate intestines of newborn babies.

Medicine & Health / Diseases, Conditions, Syndromes

created Jun 30, 2009 | popularity 3 / 5 (2) | comments 0

Study shows benefits of anti-clotting medications reduced by common heartburn drugs

The anti-clotting action of the medication clopidogrel (Plavix) can be compromised by common drugs for the treatment of heartburn and ulcers resulting in a roughly 50% increase in the combined risk of hospitalization for ...

Medicine & Health / Medications

created May 06, 2009 | popularity not rated yet | comments 0

Inhibiting proteins may prevent cartilage breakdown in arthritis patients

Current arthritis medications can ease the pain, but stopping the progression of the disease requires more aggressive treatments: use of very limited available drugs or surgical intervention. University of Missouri researchers ...

Chemistry /

created Feb 18, 2009 | popularity 4 / 5 (1) | comments 0