A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's ...
Bio & Medicine
Feb 10, 2020
0
615
Researchers from U of T Engineering have discovered that an active, rather than passive, process dictates which nanoparticles enter solid tumors. The finding upends previous thinking in the field of cancer nanomedicine and ...
Bio & Medicine
Jan 14, 2020
0
76
Personalised blood vessel testing kit could unravel causes and treatments for heart attack, stroke and vascular dementia, find scientists.
Biotechnology
Dec 9, 2019
0
28
University of Delaware researchers have discovered that lipoprotein lipase, an enzyme crucial for fat metabolism, may be contributing to wooden breast syndrome in broiler chickens.
Veterinary medicine
Nov 21, 2019
0
5
hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ...
Cell & Microbiology
Nov 4, 2019
0
46
To successfully engineer cell or tissue implants, bioengineers must facilitate their metabolic requirements through vascular regeneration. However, it is challenging to develop a broad strategy for stable and functional vascularization. ...
Surfaces that enable endothelial cell attachment without causing blood clotting are needed for various tissue engineering efforts. A new approach involving phage display has been used to identify unique peptides with these ...
Biotechnology
Jun 19, 2019
0
4
Hematopoietic stem and progenitor cells (HSPCs) give rise to all blood lineages that support life. HSPCs, like seeds, need a suitable microenvironment to maintain their function. A process called "homing" allows HSPCs to ...
Cell & Microbiology
Nov 21, 2018
0
3
Blood vessel formation relies on the ability of vascular cells to move while remaining firmly connected to each other. This enables the vessels to grow and sprout without leaking any blood. In the current issue of Nature ...
Cell & Microbiology
Sep 4, 2018
0
6
In diseases such as malaria and sickle cell disease, red blood cells break down, with harmful effects on the rest of the body – particularly the lining of small blood vessels.
Engineering
Apr 30, 2018
0
21
