First direct observation of a key molecular transport mechanism in cells challenges previous models of the process
Eukaryotic cells contain a number of compartments, each surrounded by a membrane that water-soluble molecules are unable to cross. This means that dedicated transport mechanisms are needed to move molecules ...
Gene prevents buildup of misfolded cell proteins
(Phys.org) —Much like how a snowplow is needed to clear streets of heavy snow, cells employ a set of genes to clear away misfolded proteins, to prevent them from accumulating and destroying the cell.
In search of a sugar's secrets
The discovery of the origin of enigmatic 'waste' sugar molecules within the cell also hints that they serve some as-yet-undefined function.
Mapping subcellular temperature profiles with genetically-encoded thermosensors
A protein that can mean life or death for cells
Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum (ER), which is able to sense cellular stress and trigger either ...
Biochemists discover 'parking position' of fat-burning enzymes
Fat is a curse and a blessing at the same time. While we would rather not have any fat deposits on our body, especially in summer, accumulated fats in plants are desirable as they make them especially nutritious. ...
Researchers decipher an alternative mechanism of intracellular protein trafficking
Research, published on the cover of the journal Traffic, describes existing alternative mechanisms to the traditional export model of newly synthesized membrane and secretory proteins from the endoplasmic reticu ...
Advance in re-engineering photosynthesis to make drugs, compounds or ingredients
Scientists are reporting an advance in re-engineering photosynthesis to transform plants into bio-factories that manufacture high-value ingredients for medicines, fabrics, fuels and other products. They report ...
Protein regulates protein folding in cells during stress
(Phys.org)—Cornell researchers have discovered that a protein known for moving cells around in the body also helps regulate a cellular organelle responsible for generating one-third of all proteins in the ...
Possible new route to fight dengue virus pointed
Researchers have identified enzymes and biochemical compounds called lipids that are targeted and modified by the dengue virus during infection, suggesting a potential new approach to control the aggressive ...
New insight in how cells' powerhouse divides
New research from the University of California, Davis, and the University of Colorado at Boulder puts an unexpected twist on how mitochondria, the energy-generating structures within cells, divide. The work, ...
Three-part handoff delivers proteins to membrane surface
The delivery system for an important class of proteins in the cell membrane can be fully replicated with a mere three components, according to a new study.
Aurora A may contribute to kidney disease
The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.
Protein with cardioprotective capabilities during heart attack discovered
University of Cincinnati (UC) researchers have discovered a new protein that could be cardioprotective during heart attack, potentially leading to more targeted treatments for patients at risk.