News tagged with embryonic stem cells
New technique reveals unseen information in DNA code
Imagine reading an entire book, but then realizing that your glasses did not allow you to distinguish "g" from "q." What details did you miss? Geneticists faced a similar problem with the recent discovery ...
May 17, 2012 |
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Genetic packing: Successful stem cell differentiation requires DNA compaction, study finds
(Phys.org) -- New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to ...
May 11, 2012 |
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Researchers turn skin cells into neural precusors, bypassing stem-cell stage
Mouse skin cells can be converted directly into cells that become the three main parts of the nervous system, according to researchers at the Stanford University School of Medicine. The finding is an extension of a previous ...
Jan 30, 2012 |
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Scientists create stable, self-renewing neural stem cells
In a paper published in the April 25 early online edition of the Proceedings of the National Academy of Sciences, researchers at the University of California, San Diego School of Medicine, the Gladstone Instit ...
Apr 25, 2011 |
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Critical similarity between two types of do-it-all stem cells revealed in new study
Ever since human induced pluripotent stem cells were first derived in 2007, scientists have wondered whether they were functionally equivalent to embryonic stem cells, which are sourced in early-stage embryos.
Sep 11, 2011 |
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Researchers create first human heart cells that can be paced with light
In a compact lab space at Stanford University, Oscar Abilez, MD, trains a microscope on a small collection of cells in a petri dish. A video recorder projects what the microscope sees on a nearby monitor. The cells in the ...
Sep 20, 2011 |
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Scientists convert skin cells to beating heart cells
Scripps Research Institute scientists have converted adult skin cells directly into beating heart cells efficiently without having to first go through the laborious process of generating embryonic-like stem cells. The powerful ...
Jan 31, 2011 |
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New roles emerge for non-coding RNAs in directing embryonic development
Scientists at the Broad Institute of MIT and Harvard have discovered that a mysterious class of large RNAs plays a central role in embryonic development, contrary to the dogma that proteins alone are the master regulators ...
Aug 28, 2011 |
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Human embryonic stem cells in culture created
(PhysOrg.com) -- In regenerative medicine, large supplies of safe and reliable human embryonic stem (hES) cells are needed for implantation into patients, but the field has faced challenges in developing cultures ...
Jan 25, 2011 |
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From embryonic stem cells, a sperm replacement and easier path to genetic modification
Researchers reporting in the April 27 issue of the journal Cell have devised a new and improved method for producing genetically modified animals for use in scientific research. The method relies on haploi ...
Apr 26, 2012 |
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A knockout resource for mouse genetics
An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of hum ...
Jun 15, 2011 |
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World's first chimeric monkeys are born
Researchers have produced the world's first chimeric monkeys. The bodies of these monkeys, which are normal and healthy, are composed of a mixture of cells representing as many as six distinct genomes. The ...
Jan 05, 2012 |
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Earlier, more accurate prediction of embryo survival enabled by Stanford research
Two-thirds of all human embryos fail to develop successfully. Now, in a new study, researchers at the Stanford University School of Medicine have shown that they can predict with 93 percent certainty which fertilized eggs ...
Oct 03, 2010 |
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Induced pluripotent stem cell retain an inactivated X chromosome
Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA ...
Medicine & Health / Medical research
Sep 03, 2010 |
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Stem cells reverse blindness caused by burns
(AP) -- Dozens of people who were blinded or otherwise suffered severe eye damage when they were splashed with caustic chemicals had their sight restored with transplants of their own stem cells - a stunning ...
Medicine & Health / Medical research
Jun 23, 2010 |
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Embryonic stem cell
Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells.
Embryonic Stem (ES) cells are pluripotent. This means they are able to differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes ES cells from multipotent progenitor cells found in the adult; these only form a limited number of cell types. When given no stimuli for differentiation, (i.e. when grown in vitro), ES cells maintain pluripotency through multiple cell divisions. The presence of pluripotent adult stem cells remains a subject of scientific debate; however, research has demonstrated that pluripotent stem cells can be directly generated from adult fibroblast cultures.
Because of their plasticity and potentially unlimited capacity for self-renewal, ES cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. However Diseases treated by these non-embryonic stem cells include a number of blood and immune-system related genetic diseases, cancers, and disorders; juvenile diabetes; Parkinson's; blindness and spinal cord injuries. Besides the ethical concerns of stem cell therapy (see stem cell controversy), there is a technical problem of graft-versus-host disease associated with allogeneic stem cell transplantation. However, these problems associated with histocompatibility may be solved using autologous donor adult stem cells or via therapeutic cloning.
For more information about Embryonic stem cell, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
