Mutant stem cells defy rules of development

Imagine you're baking a cake, but you run out of salt. Even with the missing ingredient, the batter still looks like cake batter, so you stick it in the oven and cross your fingers, expecting to end up with something pretty ...

Stem cells organize themselves into embryoid

Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also ...

A missing genetic switch at the origin of embryonic malformations

Embryonic development follows delicate stages: For everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more ...

Embryonic cells sense stiffness in order to form the face

Cells in the developing embryo can sense the stiffness of other cells around them, which is key to them moving together to form the face and skull, finds a new study by UCL researchers.

High-resolution mapping method for G4 DNA structures developed

While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...

New technology allows molecules to enter cells safely

Professor Kevin Braeckmans from Ghent University focused the last 10 years on a method for safe engineering of therapeutic cells with photothermal nanofibers. Today, Nature Nanotechnology gives insight in how these biocompatible ...

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