New roles emerge for non-coding RNAs in directing embryonic development
Scientists at the Broad Institute of MIT and Harvard have discovered that a mysterious class of large RNAs plays a central role in embryonic development, contrary to the dogma that proteins alone are the master regulators ...
Aug 28, 2011
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Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Aug 18, 2011
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Unraveling the mechanisms behind organ regeneration in zebrafish
The search for the holy grail of regenerative medicine -- the ability to "grow back" a perfect body part when one is lost to injury or disease -- has been under way for years, yet the steps involved in this ...
Nov 02, 2009
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The swing of architect genes
Architect genes are responsible for organizing structures of the body during embryonic development. Some of them, namely the Hox genes, are involved in the formation of forelimbs. They are activated in two successive waves, ...
Jun 06, 2013
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New X-ray method shows how frog embryos could help thwart disease
An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.
May 17, 2013
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Scientists made fundamental discovery about how properties of embryonic stem cells controlled
The study, which focuses on the process by which these cells renew and increase in number, could help research to find new treatments.
May 02, 2013
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New view of how embryos develop: Imaging technique allows researchers to see how cells form early spinal cord structures
(Phys.org) —In a factory, outside forces dictate the assembly of parts. Robots lift widgets from trays, assemble them and send them on their way. Even though embryos are not factories, theories about embryonic ...
Apr 26, 2013
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Researchers identify protein molecule used to maintain adult stem cells in fruit flies
Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining ...
Apr 22, 2013
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Timing germ cell development
(Phys.org) —Scientists from the Friedrich Miescher Institute for Biomedical Research identify a novel mechanism in early germ cell development. They show how the chromatin modulator PRC1 coordinates the ...
Mar 15, 2013
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Tiny piece of RNA keeps 'clock' running in earliest stages of life
New research shows that a tiny piece of RNA has an essential role in ensuring that embryonic tissue segments form properly.
Mar 11, 2013
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How the whale got its teeth
Whales are mammals, but they don't look like the mammals living around us, as they have a triangular fluke for tail, no hind legs and no body hair. And inside their mouths, their teeth are unfamiliar too ...
Feb 19, 2013
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Epigenetic control of cardiogenesis: Non-coding RNA is essential for normal embryonic cardiogenesis
Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. ...
Jan 29, 2013
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New study finds that one key mechanism in development involves 'paused' RNA polymerase
For a tiny embryo to grow into an entire fruit fly, mouse or human, the correct genes in each cell must turn on and off in precisely the right sequence. This intricate molecular dance produces the many parts of the whole ...
Dec 20, 2012
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The role of the cellular entry point of anthrax identified
Anthrax uses a receptor on the surface of cells to inject its lethal toxins. However, the physiological function of this receptor, named Anthrax Toxin Receptor 2a (Antxr2a), remained unknown until now.
Dec 02, 2012
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