Sterile mice produce rat sperm

Researchers generated rat sperm cells inside sterile mice using a technique called blastocyst complementation. The advance appears August 4 in the journal Stem Cell Reports.

Study finds why many IVF embryos fail to develop

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...

The black box behind embryonic development

DNA regulation is a critical process in a cell that allows it to fulfill its function. This process is key during pregnancy, when embryonic cells must develop into all cell types needed to form an embryo. An international ...

Mouse stem cells for primitive endoderm established

Stem cells that give rise to the mouse yolk sac have been isolated and cultured in the lab for the first time by RIKEN researchers, raising the possibility of artificially creating mouse embryos from stem cells in the future.

Act of sabotage determines mammalian embryonic development

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential ...

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