Piloting ribosomes past proline pairs

Certain proteins are known to require Translation Factor EF-P for their synthesis, and a new study enlarges the size of the set. As some of its members are involved in bacterial pathogenicity, the results are also of therapeutic ...

Pathogen turns protein into a virulence factor in one easy step

To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining access to human cells. ...

Study shows stressed-out cells halt protein synthesis

(Phys.org)—Cells experience stress in multiple ways. Temperature shifts, mis-folded proteins and oxidative damage can all cause cellular stress. But whatever the form of the stress, all cells quickly stop making proteins ...

Raising the blockade

At crucial points in the metabolism of all organisms, a protein with the unwieldy name of Translation Elongation Factor P (EF-P, for short) takes center stage. What it actually does during protein synthesis has only now been ...

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