3D imaging of a pelvis suggests social care for saber-tooths

You can't spell 'Smilodon fatalis' without 'fatal', but researchers at La Brea Tar Pits may have found a softer side to saber-toothed cats along with a connection to our own feline and canine companions.

Treatment with gene therapy of a new rat model of Morquio A

A research team from the Universitat Autònoma de Barcelona (UAB) has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio ...

Golden retriever study suggests neutering affects dog health

(Phys.org)—Neutering, and the age at which a dog is neutered, may affect the animal's risk for developing certain cancers and joint diseases, according to a new study of golden retrievers by a team of researchers at the ...

FANCM plays key role in inheritance

Scientists of KIT and the University of Birmingham have identified relevant new functions of a gene that plays a crucial role in Fanconi anemia, a life-threatening disease.

Light can detect pre-cancerous colon cells

After demonstrating that light accurately detected pre-cancerous cells in the lining of the esophagus, Duke University bioengineers turned their technology to the colon and have achieved similar results in a series of preliminary ...

More than 20 gene loci associated with canine hip dysplasia

An extensive study on canine hip dysplasia conforms to the polygenic background of the disease. Genes located in different chromosomes have a strong association with a protein modification process previously linked to inflammatory ...

Big dogs face more joint problems if neutered early

Heavier mixed-breed dogs have higher health risks if neutered or spayed early, according to a new study from researchers at the University of California, Davis. The study found mixed-breed dogs weighing more than 44 pounds ...

Ancient dwarfism skeleton tells story of acceptance

A remarkable 5000-year-old skeleton suggests human dwarfism was both accepted and respected in life and death in ancient China, research by a University of Otago bio-archaeologist shows.

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Dysplasia

Dysplasia (from the Greek δυσπλασία "malformation", δυσ- "mal-" + πλάθω "to create, to form"), is a term used in pathology to refer to an abnormality of development. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early neoplastic process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm.

Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with metaplasia, in which cells of one mature, differentiated type are replaced by cells of another mature, differentiated type.

The terms hip dysplasia and fibrous dysplasia also refer to abnormal development, but at a more macroscopic level.

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