News tagged with dynein
Dynein
Dynein is a motor protein (also called molecular motor or motor molecule) in cells which converts the chemical energy contained in ATP into the mechanical energy of movement. Dynein transports various cellular cargo by "walking" along cytoskeletal microtubules towards the minus-end of the microtubule, which is usually oriented towards the cell center. Thus, they are called "minus-end directed motors," while kinesins, motor proteins that move toward the microtubules' plus end, are called plus-end directed motors.
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Research links huntingtin to neurogenesis
New research finds that a protein that is often mutated in Huntington's disease (HD) plays an unexpected role in the process of neurogenesis. The research, published by Cell Press in the August 12 issue of the journal Neuron, provid ...
Medicine & Health / Neuroscience
Aug 11, 2010 |
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From wimp to jock: How a cell motor gets pushy
A University of Utah researcher helped discover how a "wimpy" protein motor works with two other proteins to gain the strength necessary to move nerve cells and components inside them. The findings shed light ...
Apr 15, 2010 |
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Stick and slide: Computer simulation advances understanding of molecular motors
A new study reveals how molecular motors that power important subcellular movements can generate cyclical motion. The research, published by Cell Press in the December issue of the Biophysical Journal, opens a new door t ...
Dec 02, 2009 |
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RNA on the move
In the fruit fly Drosophila, oskar mRNA, which is involved in defining the animal’s body axes, is produced in the nuclei of nurse cells neighbouring the oocyte, and must be transported to the oocyte and along ...
Nov 26, 2009 |
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Search results for dynein
Proteins found to spontaneously form whorls and lattices
(PhysOrg.com) -- Building on the work of a previous team that found filaments made from actin, when combined with so called motor proteins, moved themselves into distinct patterns, a new team in Japan has ...
Mar 28, 2012 |
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A mitosis mystery solved: How chromosomes align perfectly in a dividing cell
Although the process of mitotic cell division has been studied intensely for more than 50 years, Whitehead Institute researchers have only now solved the mystery of how cells correctly align their chromosomes during symmetric ...
Feb 12, 2012 |
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Molecular motor struts like drunken sailor
Monty Python may claim credit for immortalizing the “silly walk,” but molecular biology beat the comedy troupe to the punch. It turns out that a tiny motor inside of us called dynein, one tasked with shuttling vital ...
Jan 10, 2012 |
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In the brain, 'ORMOSIL' nanoparticles hold promise as a potential vehicle for drug delivery
(PhysOrg.com) -- In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain.
Nanotechnology / Bio & Medicine
Jan 09, 2012 |
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Enzyme helps control extension of cellular tendrils by regulating delivery of supplies needed for growth
The body of the adult fruit fly is covered with hair-like bristles (Fig. 1) that act as sensory organs for detecting tactile stimuli. Each one consists of a single cell that has gradually elongated over the ...
May 20, 2011 |
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Biologists capture cell's elusive 'motor' on videotape, solving the mystery of its deployment
(PhysOrg.com) -- In basic research with far-reaching impact, cell biologists Wei-Lih Lee and Steven Markus report in an article released today in Developmental Cell, with videos, that they have solved one of the fundamental questi ...
May 18, 2011 |
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Conserved kinase protects cells from endosomal traffic jam
Some molecules have a single, highly specific function in physiology, while others have a much broader remit. Kinases in the IKK (inhibitor of nuclear factor κB (NF-κB) kinase) family are of the ...
Mar 09, 2011 |
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Unraveling how prion proteins move along axons in the brain
Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) – found within many mammalian cells – up and down long, neuronal ...
Medicine & Health / Medical research
Feb 17, 2011 |
4.5 / 5 (2) |
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Protein in Huntington's linked to neurogenesis
EU-funded scientists have discovered that a mutated protein inherent in Huntington's disease (HD) performs an unforeseen role in neurogenesis. The finding could lead to a better understanding of HD, an inherited ...
Medicine & Health / Neuroscience
Sep 02, 2010 |
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Mutations that cause Parkinson's disease prevent cells from destroying defective mitochondria
Mutations that cause Parkinson's disease prevent cells from destroying defective mitochondria, according to a study published online May 10 in the Journal of Cell Biology.
May 10, 2010 |
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List of search results for dynein
