Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats.
Cell & Microbiology
Apr 8, 2024
0
48
The active ingredient in many drugs is what's known as a small molecule: bigger than water, much smaller than an antibody and mainly made of carbon. It's tough, however, to make these molecules if they require a quaternary ...
Materials Science
Apr 6, 2024
4
81
New research could pave the way to developing cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death. Cancer cells that are resistant to anticancer drugs are known to be vulnerable to ferroptosis. ...
Biotechnology
Apr 5, 2024
0
50
Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show ...
Analytical Chemistry
Apr 4, 2024
0
85
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent ...
Molecular & Computational biology
Apr 4, 2024
0
16
Micro/nanorobots, due to their small size, high controllability and precise navigation capabilities have emerged as an important tool to execute biomedical tasks in microenvironments. However, it is still a big challenge ...
Biotechnology
Apr 4, 2024
0
14
A new study has shown pollen grains can be used as green templates for producing biomaterials, showcasing their potential to support drug delivery and bone regeneration.
Biotechnology
Apr 3, 2024
0
119
A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University's Institute ...
Cell & Microbiology
Apr 3, 2024
0
0
Droplet microfluidics has revolutionized single-cell analysis, crucial for genomics, drug discovery, and diagnostics, by partitioning samples into nanoliter droplets for detailed cellular analysis. Yet, its broader adoption ...
Cell & Microbiology
Apr 1, 2024
0
84
Vanderbilt biochemists are part of a team taking a stride toward the development of antibacterials to treat uncomplicated urinary tract infections, a pervasive bacterial infection that affects 50%–60% of women in their ...
Biochemistry
Mar 28, 2024
0
78
