A highly active catalyst capable of synthesizing drug molecules within the body has been developed by RIKEN chemists. In mice, an anticancer drug assembled near tumors using the injected catalyst suppressed tumor growth.
Biochemistry
Dec 8, 2023
0
67
The building blocks for new drugs that help fight bacteria that are resistant to known antibiotics, for example, should be as cost-effective and environmentally friendly as possible. Enzymes are ideal for this purpose. For ...
Biochemistry
Dec 8, 2023
0
2
As the war in the Ukraine rages on, new research shows that hospitals there are waging a battle of their own against a different kind of enemy: antibiotic-resistant "superbugs" that are spreading at an alarming rate.
Cell & Microbiology
Dec 8, 2023
0
1
When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn't know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a ...
Analytical Chemistry
Dec 8, 2023
0
20
The Chirik Group at the Princeton Department of Chemistry is chipping away at one of the great challenges of metal-catalyzed C–H functionalization with a new method that uses a cobalt catalyst to differentiate between bonds ...
Analytical Chemistry
Dec 7, 2023
0
14
In response to the escalating challenges posed by the high drug resistance of rapidly growing mycobacteria (RGM), a collaborative team from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese ...
Cell & Microbiology
Dec 7, 2023
0
1
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
0
2
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
0
20
To the authors' knowledge, there have been no review papers that summarize the biomedical applications of heterostructures prepared by additive manufacturing. This paper aims to highlight the research progress in additive ...
Bio & Medicine
Dec 5, 2023
0
12
Exploring the biomedical interactions for chemical compounds and protein targets is crucial for drug discovery. Determining these drug–drug interactions (DDI) and drug–target interactions (DTI) not only reveals the potential ...
Molecular & Computational biology
Dec 5, 2023
0
23
