News tagged with drug targets

A single atom controls motility required for bacterial infection

Bacteria can swim, propelling themselves through fluids using a whip-like extension called a flaggella. They can also walk, strolling along solid surfaces using little fibrous legs called pili. It is this ...

Biology / Cell & Microbiology

created Jan 04, 2010 | popularity 4.9 / 5 (10) | comments 0 | with audio podcast

A fantastic voyage brought to life

Ever since the 1966 Hollywood movie, doctors have imagined a real-life Fantastic Voyage -- a medical vehicle shrunk small enough to "submarine" in and fix faulty cells in the body. Thanks to new research by ...

Nanotechnology / Bio & Medicine

created Jan 15, 2009 | popularity 4 / 5 (9) | comments 4

Team develops new weapon to fight disease-causing bacteria, malaria

Researchers report that they have discovered - and now know how to exploit - an unusual chemical reaction mechanism that allows malaria parasites and many disease-causing bacteria to survive. The research ...

Chemistry / Biochemistry

created Feb 15, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

New twist on potential malaria drug target acts by trapping parasites in cells

Harvard School of Public Health (HSPH) researchers and colleagues seeking to block invasion of healthy red blood cells by malaria parasites have instead succeeded in locking the parasites within infected blood cells, potentially ...

Medicine & Health / Medical research

created May 15, 2010 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Cells use water in nano-rotors to power energy conversion

Researchers from the Max Planck Institute of Biophysics in Frankfurt, and Mount Sinai School of Medicine in New York have provided the first atomic-level glimpse of the proton-driven motor from a major group of ATP synthases, ...

Chemistry / Biochemistry

created Aug 03, 2010 | popularity 5 / 5 (6) | comments 2 | with audio podcast

SSRIs may pack more punch at the cellular level than believed

A new discovery about selective serotonin reuptake inhibitors (SSRIs) suggests that these drugs, which are used to treat mental health disorders like depression and anxiety, have multiple effects on our cells. In a research ...

Medicine & Health / Genetics

created Aug 16, 2010 | popularity 4.7 / 5 (6) | comments 0

Scientists uncover new role for gene in maintaining steady weight

Against the backdrop of the growing epidemic of obesity in the United States, scientists from the Florida campus of The Scripps Research Institute have made an important new discovery regarding a specific gene that plays ...

Chemistry / Biochemistry

created Nov 23, 2011 | popularity 4.2 / 5 (6) | comments 2 | with audio podcast

New findings reveal how influenza virus hijacks human cells

Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability ...

Biology /

created Feb 04, 2009 | popularity 4.6 / 5 (5) | comments 0

Antibiotics improve with visualization techniques

Researchers from the Universities of Dundee and Oxford have made a significant breakthrough in understanding how resistance to antibiotics might be overcome, by producing the first ever 3D molecular image ...

Biology / Cell & Microbiology

created Jan 17, 2011 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Nanoparticles working in harmony

For decades, researchers have been working to develop nanoparticles that deliver cancer drugs directly to tumors, minimizing the toxic side effects of chemotherapy. However, even with the best of these nanoparticles, only ...

Nanotechnology / Bio & Medicine

created Jul 15, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists create potent molecules aimed at treating muscular dystrophy

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

3D structure opens new avenue for drug discovery

(PhysOrg.com) -- An international consortium has determined the structure of an important new drug target in complex with a synthetic molecule designed by our researchers, opening up new avenues for drug discovery.

Chemistry / Biochemistry

created Apr 02, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

A hot road to new drugs

The quest for new drugs is generally a lengthy and costly undertaking. German researchers of Ludwig-Maximilians-Universitaet in Munich have now come up with a simpler and more efficient way of going about it. Not only pharmaceutical ...

Chemistry / Biochemistry

created Feb 24, 2010 | popularity 4.8 / 5 (4) | comments 0

Researchers identify promising therapeutic target for central nervous system injuries

Scars can serve as double-edged swords in spinal cord injuries—saving a victim's life, but sealing his or her fate as a paraplegic or quadriplegic. The scar forms a wall around the wound, preventing the injury from spreading, ...

Medicine & Health / Medical research

created Oct 15, 2009 | popularity 5 / 5 (3) | comments 0

Combating mood disorders: New approach simplifies the search for more specific drugs

Many psychiatric conditions are caused by aberrant metabolism of the neurotransmitter serotonin. Researchers in the Department of Pharmacy at LMU have now developed a new screening method, which will facilitate the search ...

Chemistry / Biochemistry

created Sep 30, 2011 | popularity 4.7 / 5 (3) | comments 0