Taking the fight into the enemy's territory
(Phys.org) —German researchers have developed a scheme for the preparation of nanoparticles that offer a highly versatile system for targeted drug delivery directly into diverse types of tumor cells.
(Phys.org) —German researchers have developed a scheme for the preparation of nanoparticles that offer a highly versatile system for targeted drug delivery directly into diverse types of tumor cells.
Every cell of our body is separated from its environment by a lipid bilayer. In order to maintain their biological function and to transduce signals, special proteins, so called ion channels, are embedded ...
For scientists to improve cancer treatments with targeted therapeutic drugs, they need to be able to see proteins prevalent in the cancer cells. This has been an impossible, until now. Thanks to a new microscopy ...
Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent ...
A powerful computational technique used by the pharmaceutical industry to expedite new drug development has just received a performance boost. Chandra Verma and his co-workers at the A*STAR Bioinformatics ...
Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. ...
(Phys.org)—Scientists at Imperial College London have developed a system to quickly detect trace amounts of chemicals like pollutants, explosives or illegal drugs.
Researchers at Tokyo Institute of Technology and the Weizmann Institute of Science identify a means of controlling biological processes that could help treatments for immune disease, neurological disorders ...
Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make ...
Researchers at the University of Leeds have identified a crucial stage in the lifecycle of simple viruses like polio and the common cold that could open a new front in the war on viral disease.
For most of the 20th century, scientists were puzzled by how cells in our body are able to sense and react to external conditions.
Molecules with potent bioactivity alone are not suitable for new medicines. They must behave well inside the body, being easily absorbed, yet metabolically stable, once circulating through the blood stream. ...
Secretion of bacterial proteins is an essential biological process with biotechnological and biomedical impact on human health. European scientists studied a universal and widely conserved bacterial secretory ...
(Phys.org)—Biomedical scientists collaborating on translational research at two Buffalo institutions are reporting the discovery of a novel, and heretofore unrecognized, set of genes essential for the growth ...
(Phys.org)—Purdue University scientists have determined that a gene long known to be involved in cancer cell formation and chemotherapy resistance is key to proper RNA creation, an understanding that could one day lead ...