News tagged with drug resistance
Resistance to antibiotics is ancient: study
Scientists were surprised at how fast bacteria developed resistance to the miracle antibiotic drugs when they were developed less than a century ago. Now scientists at McMaster University have found that resistance has been ...
Aug 31, 2011 |
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Study shows evolutionary adaptations can be reversed, but rarely
(PhysOrg.com) -- Ever since Charles Darwin proposed his theory of evolution in 1859, scientists have wondered whether evolutionary adaptations can be reversed.
May 11, 2011 |
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See how they grow: Monitoring single bacteria without a microscope
(PhysOrg.com) -- With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of ...
Chemistry / Analytical Chemistry
Jan 17, 2011 |
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Researchers discover drug resistance mechanisms in most common form of melanoma
Researchers with UCLA's Jonsson Comprehensive Cancer Center have found that melanoma patients whose cancers are caused by mutation of the BRAF gene become resistant to a promising targeted treatment through another genetic ...
Nov 24, 2010 |
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Berkeley lab scientists reveal path to protein crystallization (w/ Video)
(PhysOrg.com) -- Growth of two-dimensional S-layer crystals on supported lipid bilayers observed in solution using in situ atomic force microscopy. This movie shows proteins sticking onto the supported lipid ...
Sep 22, 2010 |
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'Nanobubbles' plus chemotherapy equals single-cell cancer targeting
Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) ...
Nanotechnology / Bio & Medicine
Apr 09, 2012 |
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Nanoparticle-delivered RNA interference drug stops head and neck cancer growth
(Phys.org) -- A nanoparticle drug delivery vehicle for small interfering RNA molecules (siRNA), that is already being tested in human clinical trials, now shows promise for the treatment of head and neck cancer. Dong Shin, ...
Nanotechnology / Bio & Medicine
Apr 06, 2012 |
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Antibiotic resistant bacteria proliferate in agricultural soils
Infectious diseases kill roughly 13 million people worldwide, annually, a toll that continues to rise, aided and abetted by resistance genes. Now a study, published in the March Antimicrobial Agents and Chemotherapy finds ...
Mar 20, 2012 |
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Study finds how bacteria resist a 'Trojan horse' antibiotic
A new study describes how bacteria use a previously unknown means to defeat an antibiotic. The researchers found that the bacteria have modified a common "housekeeping" enzyme in a way that enables the enzyme ...
Mar 19, 2012 |
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Overcoming cancer drug resistance with nanoparticles
One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University ...
Nanotechnology / Bio & Medicine
Jan 20, 2012 |
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Research team shows cultural practices can cause biological evolution
(PhysOrg.com) -- When most people think of evolution, they think of animals growing bigger or smaller over generations due to food types or source, bacteria evolving resistance to drugs, or of humans losing their fur and ...
Other Sciences / Social Sciences
Dec 20, 2011 |
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Researchers use whole-genome sequencing to monitor evolution of drug resistance in bacteria
(PhysOrg.com) -- Two research groups working independently have come up with two different ways to use whole-genome sequencing to follow the path bacteria take in developing resistance to anti-bacterial drugs. Such research ...
Dec 19, 2011 |
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Infectious fungus, thought to be asexual, isn't: More evidence of sex in the Candida genus
The fungi of the Candida genus, known to millions of patients worldwide for their ability to cause serious infections, were once all thought to be asexual. Even after scientists discovered that the mating habits of Candid ...
Dec 05, 2011 |
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New compound defeats drug-resistant bacteria
It's no wonder that medicine's effort to combat bacterial infections is often described as an arms race. When new drugs are developed to combat infections, the bacterial target invariably comes up with a deterrent.
Nov 28, 2011 |
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Inhaled nanoparticles deliver potent anticancer cocktail to lung tumors and block resistance
(PhysOrg.com) -- An ideal treatment for lung cancer would be one that could be inhaled deep into lung tissue where it would deliver tumor-killing agents that would then largely stay in the lungs, avoiding the toxicities that ...
Nanotechnology / Bio & Medicine
Nov 21, 2011 |
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Drug resistance
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
For more information about Drug resistance, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
