News tagged with drug resistance
Medical treatments from 200 miles up
In the hunt for cancer treatments, researchers have had some help from higher authorities -- way higher. The International Space Station, orbiting the Earth at more than 200 miles in the sky, houses scientific ...
Space & Earth / Space Exploration
May 28, 2012 |
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Functional genomics gets tiny
A little more than a decade ago, researchers discovered an ancient mechanism that cells use to silence genes. Like a dimmer switch turning down a light, RNA interference (RNAi) dials down gene activity in ...
May 17, 2012 |
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Study shows evolutionary adaptations can be reversed, but rarely
(PhysOrg.com) -- Ever since Charles Darwin proposed his theory of evolution in 1859, scientists have wondered whether evolutionary adaptations can be reversed.
May 11, 2011 |
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Resistance to antibiotics is ancient: study
Scientists were surprised at how fast bacteria developed resistance to the miracle antibiotic drugs when they were developed less than a century ago. Now scientists at McMaster University have found that resistance has been ...
Aug 31, 2011 |
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See how they grow: Monitoring single bacteria without a microscope
(PhysOrg.com) -- With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of ...
Chemistry / Analytical Chemistry
Jan 17, 2011 |
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Berkeley lab scientists reveal path to protein crystallization (w/ Video)
(PhysOrg.com) -- Growth of two-dimensional S-layer crystals on supported lipid bilayers observed in solution using in situ atomic force microscopy. This movie shows proteins sticking onto the supported lipid ...
Sep 22, 2010 |
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Nanoparticle-delivered RNA interference drug stops head and neck cancer growth
(Phys.org) -- A nanoparticle drug delivery vehicle for small interfering RNA molecules (siRNA), that is already being tested in human clinical trials, now shows promise for the treatment of head and neck cancer. Dong Shin, ...
Nanotechnology / Bio & Medicine
Apr 06, 2012 |
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'Nanobubbles' plus chemotherapy equals single-cell cancer targeting
Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) ...
Nanotechnology / Bio & Medicine
Apr 09, 2012 |
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Study finds how bacteria resist a 'Trojan horse' antibiotic
A new study describes how bacteria use a previously unknown means to defeat an antibiotic. The researchers found that the bacteria have modified a common "housekeeping" enzyme in a way that enables the enzyme ...
Mar 19, 2012 |
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Antibiotic resistant bacteria proliferate in agricultural soils
Infectious diseases kill roughly 13 million people worldwide, annually, a toll that continues to rise, aided and abetted by resistance genes. Now a study, published in the March Antimicrobial Agents and Chemotherapy finds ...
Mar 20, 2012 |
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Overcoming cancer drug resistance with nanoparticles
One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University ...
Nanotechnology / Bio & Medicine
Jan 20, 2012 |
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Researchers discover drug resistance mechanisms in most common form of melanoma
Researchers with UCLA's Jonsson Comprehensive Cancer Center have found that melanoma patients whose cancers are caused by mutation of the BRAF gene become resistant to a promising targeted treatment through another genetic ...
Nov 24, 2010 |
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Antibiotics wrapped in nanofibers turn resistant disease-producing bacteria into ghosts
Encapsulating antibiotics inside nanofibers, like a mummy inside a sarcophagus, gives them the amazing ability to destroy drug-resistant bacteria so completely that scientists described the remains as mere ...
Mar 29, 2011 |
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Acne drug prevents HIV breakout (w/ Video)
Johns Hopkins scientists have found that a safe and inexpensive antibiotic in use since the 1970s for treating acne effectively targets infected immune cells in which HIV, the virus that causes AIDS, lies ...
Medicine & Health / HIV & AIDS
Mar 19, 2010 |
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Different paths to drug resistance in Leishmania
Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.
Oct 27, 2011 |
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Drug resistance
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
For more information about Drug resistance, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
