Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance. The researchers made slight changes to a small molecule to reduce its metabolism and ...
Biochemistry
Feb 28, 2023
0
73
Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of Spanish National Research Council (CSIC) have developed a series of photosensitive molecule drugs that can be reversibly activated by external light, ...
Biochemistry
Feb 16, 2023
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60
Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.
Biochemistry
Feb 8, 2023
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65
Two catalysts working in tandem enable inexpensive formate salts to perform difficult dearomative reactions, resulting in products potentially useful for drug development.
Materials Science
Feb 7, 2023
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19
Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production. Now, in a study recently published in Science, researchers ...
Analytical Chemistry
Feb 2, 2023
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123
A team of researchers at the University of Queensland has discovered some of the mechanisms involved when bacteria become more resistant to antibacterial drugs after exposure to antidepressant drugs. In their paper published ...
Using a chiral superconductor, scientists at Institute for Molecular Science and Shizuoka University have demonstrated that the magnet can distinguish right and left forms of the chiral crystal despite the common belief that ...
Condensed Matter
Jan 18, 2023
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45
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...
Cell & Microbiology
Dec 8, 2022
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56
In recent years, research and development on quantum computers has made considerable progress. Quantum chemical calculations for electronic structures of atoms and molecules are attracting great attention as one of the most ...
Analytical Chemistry
Nov 29, 2022
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158
The world's aging population, the growing burden of chronic and infectious diseases, and the emergence of novel pathogens have made the need for new treatments more urgent than ever. Yet, discovering a new drug and bringing ...
Biochemistry
Nov 16, 2022
0
40
