In drug delivery, the therapeutic behavior of the nanocarriers is limited by the "foreign" character of their surface. Despite the wide range of sophisticated coatings available, immune cells often identify these synthetic ...
Bio & Medicine
Jul 13, 2023
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31
A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine. By extracting this DNA, they were able to successfully detect ...
Bio & Medicine
Jul 3, 2023
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184
A team of researchers from the Universities of Amsterdam and Zurich together with the Swiss company Allocyte Pharmaceuticals have for the first time been able to discover allosteric sites in a type of cell surface receptor ...
Biochemistry
Jun 28, 2023
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1
Chiral molecules can present different chemical properties. For applications like drug delivery and diagnosis, it is important to detect chiral signals in mixtures. Although electronic circular dichroism (ECD) spectroscopy ...
Optics & Photonics
Jun 27, 2023
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11
Extremely intense X-ray pulses can determine the positions of some hydrogen atoms in organic molecules that form small crystals, an all-RIKEN team has shown. Many areas, including drug discovery and materials research, stand ...
Analytical Chemistry
Jun 19, 2023
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15
Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible ...
Molecular & Computational biology
Jun 8, 2023
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17
Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...
Biochemistry
Jun 7, 2023
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40
Chirality of molecules is a crucial consideration in drug development as the enantiomeric purity of a compound can significantly impact its pharmacological properties. Chiral molecules possess mirror-image enantiomers that ...
Analytical Chemistry
Jun 6, 2023
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3
A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 31, 2023
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14
Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They captured six structures ...
Cell & Microbiology
May 23, 2023
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