News tagged with drug molecules

Energy in action: For two molecules on blind date, new method predicts potential for attraction or repulsion

(Phys.org) -- Krzysztof Szalewicz, professor of physics and astronomy at the University of Delaware, and Rafal Podeszwa of the University of Silesia Institute of Chemistry in Poland have developed and validated ...

Chemistry / Materials Science

created May 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Research team gives drug dropouts a second chance

(Phys.org) -- A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly ...

Chemistry / Biochemistry

created May 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

The presence of water changes the structure of an antibiotic

EPFL chemists have shown how the three-dimensional shape of an antibiotic changes when it is in an aqueous environment. This could lead to a better understanding of how drugs interact with biological molecules.

Chemistry / Biochemistry

created Apr 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Nanoparticle-delivered RNA interference drug stops head and neck cancer growth

(Phys.org) -- A nanoparticle drug delivery vehicle for small interfering RNA molecules (siRNA), that is already being tested in human clinical trials, now shows promise for the treatment of head and neck cancer. Dong Shin, ...

Nanotechnology / Bio & Medicine

created Apr 06, 2012 | popularity 5 / 5 (8) | comments 1 | with audio podcast

3D structure opens new avenue for drug discovery

(PhysOrg.com) -- An international consortium has determined the structure of an important new drug target in complex with a synthetic molecule designed by our researchers, opening up new avenues for drug discovery.

Chemistry / Biochemistry

created Apr 02, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Sea sponge potential source of new medicines

The sea sponge has provided Flinders University researchers with inspiration for the discovery and development of new therapeutic agents in the treatment of infectious diseases and cancers.

Chemistry / Biochemistry

created Feb 28, 2012 | popularity 5 / 5 (2) | comments 0

Biology-oriented synthesis (BIOS) - cancer drugs based on natural models

The search for new drug candidates for cancer treatment is laborious and time-consuming. Only a fraction of the promising chemical compounds identified completes the transition to the market. Herbert Waldmann ...

Chemistry / Biochemistry

created Feb 28, 2012 | popularity 5 / 5 (1) | comments 0

Mapping of protein inhibitors facilitates development of tailor-made anticancer agents

(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...

Biology / Biotechnology

created Feb 20, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New dye could open the door to in vivo applications of fluorescence anisotropy

(PhysOrg.com) -- US scientists have synthesized a polymethine dye that can be used for fluorescence anisotropy imaging in the near-infrared (NIR) spectral range, making new in vivo applications of this technique ...

Chemistry / Analytical Chemistry

created Feb 17, 2012 | popularity not rated yet | comments 0

Record reaction cascade yields cancer drug candidate

(PhysOrg.com) -- New active substances can be produced quickly and efficiently with the help of reaction cascades. Once set in motion, these processes lead to the desired end product via a series of intermediate steps which ...

Chemistry / Biochemistry

created Dec 26, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers develop CAD-Type tools for engineering RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the Joint BioEnergy ...

Biology / Biotechnology

created Dec 22, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Silk microneedles deliver controlled-release drugs painlessly

Bioengineers at Tufts University School of Engineering have developed a new silk-based microneedle system able to deliver precise amounts of drugs over time and without need for refrigeration. The tiny needles can be fabricated ...

Chemistry / Materials Science

created Dec 21, 2011 | popularity 4.8 / 5 (5) | comments 2 | with audio podcast

Scientists develop new class of small molecules through innovative chemistry

Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery.

Chemistry / Biochemistry

created Nov 20, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Molecules on branched-polymer surfaces can capture rare tumor cells in blood

The removal of rare tumor cells circulating in the blood might be possible with the use of biomolecules bound to dendrimers, highly branched synthetic polymers, which could efficiently sift and capture the diseased cells, ...

Chemistry / Biochemistry

created Nov 17, 2011 | popularity not rated yet | comments 0 | with audio podcast

Nano-tech makes medicine greener

Over the last 5 years the Bionano Group at the Nano-Science Center and the Department of Neuroscience and Pharmacology at the University of Copenhagen has been working hard to characterise and test how molecules react, combine ...

Nanotechnology / Bio & Medicine

created Nov 03, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast