Anthrax targets
A trawl of the genome of the deadly bacterium Bacillus anthracis has revealed a clutch of targets for new drugs to combat an epidemic of anthrax or a biological weapons attack. The targets are all proteins that are found ...
Aug 20, 2012
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The mystery of protein folding: Nobel laureate summarizes his insights into the physical backgrounds
Living subjects are very complex systems and, at the same time, stunningly robust and accommodative. The secret of success are their proteins which build up the cells of the organisms, act as cleaners, messengers, ...
Aug 14, 2012
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The modeling of new enzymes helps develop therapies for cocaine abuse
Molecules with rare and valuable light-absorbing abilities finally give up their structural secrets
Potential applications for organic molecules that can interact with light in unusual ways range from next-generation solar cells to light-activated anticancer drugs. One of the oldest families of these brightly ...
Jul 06, 2012
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High-yield selective synthesis of specific molecules
Organic chemists seek synthesis reactions that produce high yields of very pure products. European researchers have developed novel synthetic reactions for a class of compounds particularly relevant to potential ...
Jul 06, 2012
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1 million billion billion billion billion billion billion: Number of undiscovered drugs
Nanoscale protein containers could aid drug, vaccine delivery
UCLA biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the ...
May 31, 2012
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Energy in action: For two molecules on blind date, new method predicts potential for attraction or repulsion
(Phys.org) -- Krzysztof Szalewicz, professor of physics and astronomy at the University of Delaware, and Rafal Podeszwa of the University of Silesia Institute of Chemistry in Poland have developed and validated ...
May 16, 2012
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Research team gives drug dropouts a second chance
(Phys.org) -- A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly ...
May 07, 2012
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The presence of water changes the structure of an antibiotic
EPFL chemists have shown how the three-dimensional shape of an antibiotic changes when it is in an aqueous environment. This could lead to a better understanding of how drugs interact with biological molecules.
Apr 20, 2012
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Nanoparticle-delivered RNA interference drug stops head and neck cancer growth
(Phys.org) -- A nanoparticle drug delivery vehicle for small interfering RNA molecules (siRNA), that is already being tested in human clinical trials, now shows promise for the treatment of head and neck cancer. Dong Shin, ...
Apr 06, 2012
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3D structure opens new avenue for drug discovery
(PhysOrg.com) -- An international consortium has determined the structure of an important new drug target in complex with a synthetic molecule designed by our researchers, opening up new avenues for drug discovery.
Apr 02, 2012
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Sea sponge potential source of new medicines
The sea sponge has provided Flinders University researchers with inspiration for the discovery and development of new therapeutic agents in the treatment of infectious diseases and cancers.
Feb 28, 2012
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Biology-oriented synthesis (BIOS) - cancer drugs based on natural models
The search for new drug candidates for cancer treatment is laborious and time-consuming. Only a fraction of the promising chemical compounds identified completes the transition to the market. Herbert Waldmann ...
Feb 28, 2012
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