Blocking the active site of thiolase

Scientists at the University of Oulu, Finland, and at the Helmholtz Center Berlin (HZB) have shown the way to new directions in drug development against African sleeping sickness and other tropical parasitic infections. This ...

A protein provides stress relief for cells

German researchers have shown a new mechanism via which cells defend themselves against stress. Dr. Kathrin Thedieck and Birgit Holzwarth from the Institute of Biology III and the Cluster of Excellence BIOSS Centre for Biological ...

New bioengineering prof uncovers cancer metabolism insights

(PhysOrg.com) -- Research from a new member of the bioengineering faculty at the UC San Diego Jacobs School of Engineering demonstrates that our cells metabolize nutrients in a very different manner than has long been thought. ...

Understanding the APJ Receptor Binding Site

(PhysOrg.com) -- Apelin is a recently discovered peptide that binds to the apelin (or APJ) G-protein-coupled receptor. Apelin-13 (NH2-QRPRLSHKGPMPF-COOH), one of several cleavage products of the proprotein form of the apelin ...

Single-cell test can reveal precisely how drugs kill cancer cells

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D2O-probed ...

The sweet taste of innovation

Would that ice-cold bottle of soda taste as refreshing, knowing that it contains 65 grams (5 tablespoons) of added sugar? With a new U.S. food-labeling policy set to kick in, public health groups are banking on the answer ...

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