News tagged with drug metabolism

Understanding the APJ Receptor Binding Site

(PhysOrg.com) -- Apelin is a recently discovered peptide that binds to the apelin (or APJ) G-protein-coupled receptor. Apelin-13 (NH2-QRPRLSHKGPMPF-COOH), one of several cleavage products of the proprotein form of the apelin ...

dateJun 01, 2010 in Biochemistry
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DCA research on brain cancer

Medical Researchers at the University of Alberta reported today evidence that the orphan generic drug Dichloroacetate (DCA) may hold promise as potential therapy for perhaps the deadliest of all human cancers: a form of brain ...

dateMay 12, 2010 in Cancer
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New way to lose fat, keep the lean

Researchers reporting in the February 3rd issue of Cell Metabolism may have a new way to trick the body into consuming more energy. The target in this case is an enzyme that indirectly controls the activity of what the researchers ...

dateFeb 02, 2010 in Medical research
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Upending textbook science on Alzheimer's disease

Alzheimer's disease is caused by the build-up of a brain peptide called amyloid-beta. That's why eliminating the protein has been the focus of almost all drug research pursuing a cure for the devastating neurodegenerative ...

dateNov 23, 2009 in Neuroscience
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