Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery.
Nov 20, 2011
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(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer ...
Aug 03, 2009
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The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in ...
May 07, 2013
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(Phys.org) -- A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly ...
May 07, 2012
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Scientists from the School of Pharmacy at Queen's University Belfast and Almac Discovery Ltd have developed a new treatment for cancer which rather than attacking tumours directly, prevents the growth of new blood vessels ...
Apr 05, 2011
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Researchers have discovered a promising new malaria drug with the potential to treat resistant strains of the deadly disease in a single dose, according to a study published Thursday in the journal Science.
Sep 02, 2010
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The devastating, currently incurable motor-neuron disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs).
Jul 12, 2010
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(PhysOrg.com) -- Some drugs may be more effective the longer they last inside the body. To prevent such drugs from being broken down too rapidly, pharmaceutical manufacturers often attach a fluorine-containing ...
Jun 24, 2010
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(PhysOrg.com) -- A robust new technique for screening drugs' effects on zebrafish behavior is pointing Harvard University scientists toward unexpected compounds and pathways that may govern sleep and wakefulness ...
Jan 14, 2010
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(PhysOrg.com) -- Researchers at the University of Michigan's Life Sciences Institute have developed a new method to rapidly generate and test novel antibiotic-drug candidates. The technique could provide scientists ...
Jan 11, 2010
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A Nobel-winning process for testing new drugs to treat diseases such as Huntington's, Parkinson's, and muscular dystrophy is getting an electrical charge.
Jan 05, 2010
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(PhysOrg.com) -- Viruses like Hepatitis C proliferate by tricking cellular machinery into manufacturing the parts for duplicate viral particles.
Sep 30, 2009
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A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell ...
Aug 27, 2009
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A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer's disease pathology has been discovered by researchers at the University of ...
Aug 10, 2009
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