News tagged with drug candidate
Research team gives drug dropouts a second chance
(Phys.org) -- A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly ...
May 07, 2012 |
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Scientists develop new class of small molecules through innovative chemistry
Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery.
Nov 20, 2011 |
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Scientists discover a way to kill off tumors in cancer treatment breakthrough
Scientists from the School of Pharmacy at Queen's University Belfast and Almac Discovery Ltd have developed a new treatment for cancer which rather than attacking tumours directly, prevents the growth of new blood vessels ...
Apr 05, 2011 |
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New microchip technology performs 1,000 chemical reactions at once
(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer ...
Chemistry / Analytical Chemistry
Aug 03, 2009 |
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Drug discovery, Netflix style?
(PhysOrg.com) -- In the last 10 years, the growth of the Internet has made ranking algorithms one of the hottest topics in computer science. The most famous ranking algorithm is Google's, which determines ...
Apr 14, 2010 |
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Promising new one-dose malaria drug discovered
Researchers have discovered a promising new malaria drug with the potential to treat resistant strains of the deadly disease in a single dose, according to a study published Thursday in the journal Science.
Medicine & Health / Medications
Sep 02, 2010 |
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'Fatostatin' is a turnoff for fat genes
A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell ...
Aug 27, 2009 |
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Outsmarting bacteria: Researchers develop faster method to generate new antibiotics
(PhysOrg.com) -- Researchers at the University of Michigan's Life Sciences Institute have developed a new method to rapidly generate and test novel antibiotic-drug candidates. The technique could provide scientists ...
Jan 11, 2010 |
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Electric field propels worms to test new drugs
A Nobel-winning process for testing new drugs to treat diseases such as Huntington's, Parkinson's, and muscular dystrophy is getting an electrical charge.
Jan 05, 2010 |
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A Twist in the Genome Thwarts Hepatitis C
(PhysOrg.com) -- Viruses like Hepatitis C proliferate by tricking cellular machinery into manufacturing the parts for duplicate viral particles.
Sep 30, 2009 |
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Biology-oriented synthesis (BIOS) - cancer drugs based on natural models
The search for new drug candidates for cancer treatment is laborious and time-consuming. Only a fraction of the promising chemical compounds identified completes the transition to the market. Herbert Waldmann ...
Feb 28, 2012 |
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Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologs while sparing paralogous pr
(Phys.org) -- New drug candidates require testing in animal models prior to approval for clinical use. A recently developed antagonist based on a bicyclic peptide inhibited the human serine protease plasma ...
Apr 13, 2012 |
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Potent screening tool finds new roles for some drugs in rest, waking
(PhysOrg.com) -- A robust new technique for screening drugs' effects on zebrafish behavior is pointing Harvard University scientists toward unexpected compounds and pathways that may govern sleep and wakefulness ...
Jan 14, 2010 |
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Researchers demonstrate efficacy of antisense therapy for spinal muscular atrophy
The devastating, currently incurable motor-neuron disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs).
Jul 12, 2010 |
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New class of compounds discovered for potential Alzheimer's disease drug
A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer's disease pathology has been discovered by researchers at the University of ...
Aug 10, 2009 |
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