Related topics: cancer cells

A fail-safe mechanism for DNA repair

Single-molecule fluorescent measurements provide fresh insights into a process for keeping errors out of our genomes.

Time to step inside your DNA

Researchers at the MRC Weatherall Institute of Molecular Medicine (MRC WIMM) have developed technology that allows scientists to explore the complex 3-D structure of DNA in Virtual Reality. In a newly published pre-print, ...

Tying the knot: New DNA nanostructures

Knots are indispensable tools for such human activities as sailing, fishing and rock climbing, (not to mention, tying shoes). But tying a knot in a lacelike strand of DNA, measuring just billionths of a meter in length, requires ...

The periodic motion of flexible knots, and the connection to DNA

Can the topology of microobjects influence the way they move in a fluid? Experiments and simulations of Polish and Swiss researchers published in the Physical Review Letters show that the dynamics of elastic chains settling ...

Supercoil me! The art of knotted DNA maintenance

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. Researchers now suggest that the DNA propensity to be supercoiled, just ...

Built for speed: DNA nanomachines take a (rapid) step forward

When it comes to matching simplicity with staggering creative potential, DNA may hold the prize. Built from an alphabet of just four nucleic acids, DNA provides the floorplan from which all earthly life is constructed.

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