News tagged with dna sequence variation
Different paths to drug resistance in Leishmania
Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.
Oct 27, 2011 |
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Evolution led to genetic variation that may affect diabetes, scientist says
The root causes of complex diseases such as type-2 diabetes and obesity have been difficult to identify because the diseases are, well, complex. They occur at the dicey biological intersection of genes and environment, and, ...
Feb 07, 2011 |
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Scientists describe new approach for identifying genetic markers for common diseases
A group of researchers at The Scripps Research Institute and the Scripps Translational Science Institute has published a paper that reviews new strategies for identifying collections of rare genetic variations that reveal ...
Oct 28, 2010 |
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Finding variants in the human genome: HapMap 3 points the way forward for human genetics studies
New findings show the value of genetic studies across human populations and the value of the latest DNA sequencing technologies to interrogate genetic variation. The results, from the latest phase of the international HapMap ...
Sep 01, 2010 |
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Enhancer of prostate cancer risk located in gene desert
A genetic variant implicated in several cancers by genome-wide association studies (GWAS) has been found to drive increased expression of a known oncogene in the prostate.
Jul 12, 2010 |
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Hypertensive rat genome sequence expected to uncover genetic basis of human hypertension
Chronic high blood pressure, also known as hypertension, is a serious health risk factor that afflicts more than 25% of all adults worldwide, but the molecular basis of the disease remains poorly understood. In a study published ...
Apr 28, 2010 |
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What makes us unique? Not genes so much as surrounding sequences
The key to human individuality may lie not in our genes, but in the sequences that surround and control them, according to new research by scientists at the Stanford University School of Medicine and Yale ...
Mar 18, 2010 |
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Sequencing genome of entire family reveals parents give kids fewer gene mutations than was thought
Researchers at the University of Utah and other institutions have sequenced for the first time the entire genome of a family, enabling them to accurately estimate the average rate at which parents pass genetic mutations to ...
Mar 10, 2010 |
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Study finds genetic link between misery and death
In ongoing work to identify how genes interact with social environments to impact human health, UCLA researchers have discovered what they describe as a biochemical link between misery and death. In addition, they found a ...
Feb 24, 2010 |
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Epigenetic signals differ across alleles
Researchers from the Institute of Psychiatry (IoP), King's College London, have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either ...
Feb 12, 2010 |
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Gene Testing In the Doctors Office
(PhysOrg.com) -- A portable instrument manufactured by Nanosphere Inc. and recently approved by the FDA, can detect genetic variations in blood that alter the effectiveness of some drugs.
Nanotechnology / Bio & Medicine
Dec 02, 2009 |
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Scientists develop new method to detect copy number variants using DNA sequencing technologies
A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive and accurate way of identifying gene copy number variations (CNVs). The method, which is ...
Aug 24, 2009 |
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Researchers sequence exomes of 12 people (w/ Video)
In a pioneering effort that generated massive amounts of DNA sequence data from 12 people, a team supported by the National Institutes of Health (NIH) has demonstrated the feasibility and value of a new strategy for identifying ...
Aug 16, 2009 |
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Researchers discover evolutionary event underlying the origin of dachshunds, dogs with short legs
A single evolutionary event appears to explain the short, curved legs that characterize all of today's dachshunds, corgis, basset hounds and at least 16 other breeds of dogs, a team led by the National Human ...
Jul 16, 2009 |
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Domestication of Capsicum annuum chile pepper provides insights into crop origin and evolution
Without the process of domestication, humans would still be hunters and gatherers, and modern civilization would look very different. Fortunately, for all of us who do not relish the thought of spending our ...
Jun 19, 2009 |
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