(Phys.org)—Is it possible to engineer self-replicating nanomaterials? It could be if we borrow nature's building blocks. DNA is a self-replicating molecule where its component parts, nucleotides, have specific chemical ...
The molecular machines that copy DNA in a living cell are amazingly fast and accurate at pairing up the correct bases—G with C and A with T—into each new double helix.
Biochemistry
Mar 11, 2015
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Ribonucleotides, units of RNA, can become embedded in genomic DNA during processes such as DNA replication and repair, affecting the stability of the genome by contributing to DNA fragility and mutability. Scientists have ...
Biotechnology
Jan 26, 2015
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(PhysOrg.com) -- A new report published in the journal Nature describes the new machine created by Jonathan Rothberg of Ion Torrent Systems which uses semiconductors to decode DNA and takes them one step closer to being able ...
DNA contains all of the genetic instructions that make us who we are, and maintaining the integrity of our DNA over the course of a lifetime is a critical, yet complex part of the aging process. In an important, albeit early ...
Biochemistry
Mar 18, 2011
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(PhysOrg.com) -- Important molecular machines routinely crash into one another while plying their trades on DNA. New research shows that the enzymes that copy DNA before cell division, called replisomes, are the kings of ...
Cell & Microbiology
Feb 10, 2010
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An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism ...
Cell & Microbiology
Apr 22, 2024
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Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Cell & Microbiology
Apr 17, 2024
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145
When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which ...
Cell & Microbiology
Mar 29, 2024
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131
Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's state-of-the-art instrumentation ...
Cell & Microbiology
Mar 18, 2024
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