Researchers discover that protein switches functions to regulate DNA replication
One protein. One mechanism of action. Two biologically opposite effects.
Biotechnology
Jul 23, 2021
0
2249
News tagged with dna replication
Gene editing 'blocks virus transmission' in human cells
Scientists have used CRISPR gene-editing technology to successfully block the transmission of the SARS-CoV-2 virus in infected human cells, according to research released Tuesday that could pave the way for COVID-19 treatments.
Biotechnology
Jul 13, 2021
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978
Cohesin opens up for cell division
Scientists at Nagoya University, with colleagues at Kyoto University in Japan, have uncovered a mechanism that allows a protein complex to bind to DNA without impeding some of the important processes of cell division. Their ...
Cell & Microbiology
Jun 22, 2021
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9
Successful DNA replication in cyanobacteria depends on the circadian clock
A new study from the University of Chicago has found that the photosynthetic bacterium Synechococcus elongatus uses a circadian clock to precisely time DNA replication, and that interrupting this circadian rhythm prevents ...
Cell & Microbiology
May 11, 2021
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607
Biologists discover a trigger for cell extrusion
For all animals, eliminating some cells is a necessary part of embryonic development. Living cells are also naturally sloughed off in mature tissues; for example, the lining of the intestine turns over every few days.
Cell & Microbiology
May 5, 2021
0
114
Sixty-year-old question on DNA replication timing sequence answered
Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program," a process that controls when and in what order segments ...
Molecular & Computational biology
Apr 23, 2021
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1241
An international study reveals how the 'guardian' of the genome works
Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre (CNIO) have discovered how certain proteins ensure the repair of errors introduced ...
Molecular & Computational biology
Apr 6, 2021
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261
Researchers shed new light on DNA replication
In preparation for cell division, cells need to replicate the DNA that they contain. A team of researchers from TU Delft, collaborating with investigators from the Francis Crick Institute in London, has now shown that the ...
Cell & Microbiology
Mar 30, 2021
0
167
How human cells coordinate the start of DNA replication
Cold Spring Harbor Laboratory (CSHL) President and CEO Bruce Stillman has been dissecting DNA replication, a critical step in cell division, since the 1980s. His lab studies how Origin Recognition Complexes—ORCs—coordinate ...
Molecular & Computational biology
Mar 23, 2021
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189
Research pinpoints unique drug target in antibiotic resistant bacteria
Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics.
Biochemistry
Mar 8, 2021
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140
