Decoding the role of CSB protein in DNA repair

Using the Summit supercomputer at the U.S. Department of Energy's (DOE's) Oak Ridge National Laboratory (ORNL), a Georgia State University (GSU) research team has revealed the structural mechanism of the Cockayne Syndrome ...

Advancing genome editing through studying DNA repair mechanisms

Since the discovery of CRISPR/Cas9, also known as molecular scissors, scientists around the world have been working to improve the revolutionary technique for altering DNA that earned Emmanuelle Charpentier and Jennifer Doudna ...

Microorganism sheds new light on cancer resistance

A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another ...

Developing tools to visualize DNA repair as never before

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...

The role of messenger RNA in DNA repair

An organism's genome could be compared to a complex system of instructions that allows it not only to develop, but also to carry out all the activities essential to its survival. To do this, this genome needs to be expressed ...

Solving a long-standing biological search problem

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university ...

page 7 from 27