News tagged with dna polymerase

Scientists observe single gene activity in living cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...

Biology / Biotechnology

created Apr 21, 2011 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Scientists crash test DNA's replication machinery

(PhysOrg.com) -- Important molecular machines routinely crash into one another while plying their trades on DNA. New research shows that the enzymes that copy DNA before cell division, called replisomes, are the kings of ...

Biology / Cell & Microbiology

created Feb 10, 2010 | popularity 5 / 5 (9) | comments 1 | with audio podcast

Chemists Discover How Cells Create Stability During Critical DNA-to-RNA Information Transfers

(PhysOrg.com) -- A pair of University of Massachusetts Amherst chemists believe they have for the first time explained how the main players in transcription -- RNA polymerase, RNA (red in illustration) and ...

Chemistry / Biochemistry

created Dec 29, 2009 | popularity 4.6 / 5 (12) | comments 0

'Sloppier copier' surprisingly efficient

The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.

Biology / Cell & Microbiology

created Jul 15, 2009 | popularity 4.3 / 5 (4) | comments 3

Everything flows in rapid diagnostic tests

(Phys.org) -- Our ability to detect pathogens has become quite good, but it usually requires complex laboratory techniques. Sometimes we need a quick result, or there is no laboratory nearby. Portable and ...

Chemistry / Analytical Chemistry

created Apr 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Biologists offer clearer picture of how protein machine systems tweak gene expression

Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case ...

Biology / Biotechnology

created Mar 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study uncovers how DNA unfolds for transcription

(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...

Biology / Cell & Microbiology

created Jan 17, 2012 | popularity 5 / 5 (4) | comments 5 | with audio podcast

Want to silence a gene? Pull here

(PhysOrg.com) -- Simply stretching DNA can silence a gene, scientists at the UA have discovered. The finding could point to a previously unknown gene control mechanism.

Biology / Biotechnology

created Mar 21, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Stop and go: How the cell deals with transcriptional roadblocks

Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...

Biology / Cell & Microbiology

created Feb 23, 2011 | popularity not rated yet | comments 0 | with audio podcast

Chaperone enzyme provides new target for cancer treatments

UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads ...

Biology / Cell & Microbiology

created Jan 18, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists ID new cancer drug target

Suppressing cancer cells' ability to replicate damaged DNA could dramatically enhance the effectiveness of chemotherapy drugs such as cisplatin, according to a new pair of papers from MIT biologists.

Medicine & Health / Cancer

created Nov 08, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

DNA repair changes with the flip of a switch

(PhysOrg.com) -- The DNA blueprint in each human cell undergoes about 100,000 damaging events every day. Because a cell's survival depends on the repair of these damaged molecules, each injury signals a team ...

Chemistry / Biochemistry

created Aug 26, 2010 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Correcting a trick of the light brings molecules into view

Conventional wisdom holds that optical microscopy can't be used to "see" something as small as an individual molecule. But as it is wont, clever science has once again overturned conventional wisdom. Secretary ...

Nanotechnology / Nanophysics

created Jul 14, 2010 | popularity 5 / 5 (20) | comments 1 | with audio podcast

Researchers find structural basis for incidence of skin cancers in a genetic disorder

Researchers from Mount Sinai School of Medicine have found why patients with a variant form of xeroderma pigmentosum (XPV), an inherited genetic disorder characterized by extreme sensitivity to the sun, are more susceptible ...

Medicine & Health / Medical research

created Jun 23, 2010 | popularity not rated yet | comments 0 | with audio podcast

How the wrong genes are repressed

The mechanism by which 'polycomb' proteins critical for embyronic stem cell function and fate are targeted to DNA has been identified by UCL scientists.

Biology / Cell & Microbiology

created Jun 11, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast