News tagged with dna polymerase
Scientists observe single gene activity in living cells
Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...
Apr 21, 2011 |
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Scientists crash test DNA's replication machinery
(PhysOrg.com) -- Important molecular machines routinely crash into one another while plying their trades on DNA. New research shows that the enzymes that copy DNA before cell division, called replisomes, are the kings of ...
Feb 10, 2010 |
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Chemists Discover How Cells Create Stability During Critical DNA-to-RNA Information Transfers
(PhysOrg.com) -- A pair of University of Massachusetts Amherst chemists believe they have for the first time explained how the main players in transcription -- RNA polymerase, RNA (red in illustration) and ...
Dec 29, 2009 |
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'Sloppier copier' surprisingly efficient
The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.
Jul 15, 2009 |
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Everything flows in rapid diagnostic tests
(Phys.org) -- Our ability to detect pathogens has become quite good, but it usually requires complex laboratory techniques. Sometimes we need a quick result, or there is no laboratory nearby. Portable and ...
Chemistry / Analytical Chemistry
Apr 12, 2012 |
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Biologists offer clearer picture of how protein machine systems tweak gene expression
Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case ...
Mar 01, 2012 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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Want to silence a gene? Pull here
(PhysOrg.com) -- Simply stretching DNA can silence a gene, scientists at the UA have discovered. The finding could point to a previously unknown gene control mechanism.
Mar 21, 2011 |
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Stop and go: How the cell deals with transcriptional roadblocks
Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Feb 23, 2011 |
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Chaperone enzyme provides new target for cancer treatments
UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads ...
Jan 18, 2011 |
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Scientists ID new cancer drug target
Suppressing cancer cells' ability to replicate damaged DNA could dramatically enhance the effectiveness of chemotherapy drugs such as cisplatin, according to a new pair of papers from MIT biologists.
Nov 08, 2010 |
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DNA repair changes with the flip of a switch
(PhysOrg.com) -- The DNA blueprint in each human cell undergoes about 100,000 damaging events every day. Because a cell's survival depends on the repair of these damaged molecules, each injury signals a team ...
Aug 26, 2010 |
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Correcting a trick of the light brings molecules into view
Conventional wisdom holds that optical microscopy can't be used to "see" something as small as an individual molecule. But as it is wont, clever science has once again overturned conventional wisdom. Secretary ...
Jul 14, 2010 |
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Researchers find structural basis for incidence of skin cancers in a genetic disorder
Researchers from Mount Sinai School of Medicine have found why patients with a variant form of xeroderma pigmentosum (XPV), an inherited genetic disorder characterized by extreme sensitivity to the sun, are more susceptible ...
Medicine & Health / Medical research
Jun 23, 2010 |
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How the wrong genes are repressed
The mechanism by which 'polycomb' proteins critical for embyronic stem cell function and fate are targeted to DNA has been identified by UCL scientists.
Jun 11, 2010 |
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