DNA repair scheme gets closer look for cancer therapy

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, Have taken a close look at one of the ways cells repair broken strands of DNA and discovered details that could help make a ...

CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

A building block for liver fitness in old age

The liver can regenerate even in old age and remains surprisingly fit, even though the chromatin in its cells undergoes major remodeling due to epigenetic changes, as researchers from the Max Planck Institute for Biology ...

Researchers chart advances in ancient DNA technology

Over the past 10 years, researchers led by Fu Qiaomei from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences (CAS) have used ancient DNA (aDNA) technology to unearth ...

Team develops automated platform for plasmid production

Plasmids have extensive use in basic and applied biology. These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in the production of therapeutic ...

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