'Sloppier copier' surprisingly efficient
The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.
Cell & Microbiology
Jul 15, 2009
3
0
News tagged with dna mutation
Humans are reason for why domestic animals have strange and varied coat colors
(Physorg.com) -- Humans have actively changed the coats of domestic animals by cherry-picking rare genetic mutations, causing variations such as different colours, bands and spots, according to a new study.
Jan 16, 2009
5
0
An evolutionary mystery 125 million years in the making
Plant genomics has come a long way since Cold Spring Harbor Laboratory (CSHL) helped sequence the first plant genome. But engineering the perfect crop is still, in many ways, a game of chance. Making the same DNA mutation ...
Molecular & Computational biology
Mar 4, 2024
0
249
Scientists create artificial DNA that can be transcribed by a natural enzyme
The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it's possible to add more letters to this alphabet ...
Biotechnology
Dec 14, 2023
0
64
Testing the limits of AlphaFold2's accuracy in predicting protein structure
Proteins, the workhorses of biology, are encoded by DNA sequences and are responsible for vital functions within cells. Since the first experimental measurement of a protein structure was made by John Kendrew in the 1950s, ...
Biotechnology
Nov 22, 2023
0
67
A NICER approach to genome editing
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...
Biotechnology
Sep 15, 2023
0
58
Researchers describe a 'POT-hole' that protects our chromosome ends
Researchers have determined a new feature of how the natural ends of our chromosomes are protected from harmful outcomes.
Cell & Microbiology
Aug 17, 2023
0
164
New method brings increased efficiency, precision and reliability in DNA editing
In a new study published in Nature Methods, researchers at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, describe improvements in the methods with which mutations can be introduced in human and ...
Biotechnology
Jul 20, 2023
0
82
DNA-repair protein complex is a shapeshifter, reconfiguring itself to meet the demands of each task
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic ...
Cell & Microbiology
Jul 10, 2023
0
92
Study in mice links heat-damaged DNA in food to possible genetic risks
Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA ...
Biochemistry
Jun 13, 2023
0
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