The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...
Biotechnology
Sep 15, 2023
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58
A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. In a report receiving advance online publication in Nature Biotechnology, Massachusetts General Hospital (MGH) investigators describe ...
Biotechnology
Jan 26, 2014
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0
Most mutations in the genes of the Salmonella bacterium have a surprisingly small negative impact on bacterial fitness. And this is the case regardless whether they lead to changes in the bacterial proteins or not. This is ...
Cell & Microbiology
Nov 5, 2010
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1
A study led by Indiana University biologist Patricia Foster and colleagues has found that forces in the external environment and oxidation are the greatest threats to an organism's ability to repair damage to its own DNA.
Cell & Microbiology
Oct 13, 2015
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491
A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered. ...
Biotechnology
Nov 21, 2017
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70
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
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80
A study led by scientists from the Royal Botanic Gardens, Kew's Jodrell Laboratory, which focuses on epigenetics in European common marsh orchids, has revealed that some plants may be able to adapt more quickly to environmental ...
Evolution
Aug 10, 2010
4
0
Sequencing the first human genome was a herculean effort that took 13 years, hundreds of researchers around the globe and billions of dollars.
Biotechnology
Jun 17, 2019
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61
Males that face tougher competition for females risk having offspring with a greater number of harmful mutations in their genome than males without rivals. Researchers at Uppsala University have discovered this correlation ...
Plants & Animals
Mar 16, 2020
1
228
It is nothing short of a world record in DNA research that scientists at the Centre for GeoGenetics at the Natural History Museum of Denmark (University of Copenhagen) have hit. They have sequenced the so far oldest genome ...
Biotechnology
Jun 26, 2013
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