DNA sequence symmetries from maximum entropy: The origin of the Chargaff's second parity rule
Most living organisms rely on double-stranded DNA to perpetuate their genetic code. This biological information is the main target of evolution.
Most living organisms rely on double-stranded DNA to perpetuate their genetic code. This biological information is the main target of evolution.
Biotechnology
May 15, 2020
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1007
The DNA molecule is chemically unstable, giving rise to DNA lesions of various kinds. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. The DNA damage response ...
Cell & Microbiology
Mar 31, 2015
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1773
Remarkably, living cells are able to package a jumble of DNA over two meters in length into tidy, tiny chromosomes while preparing for cell division. However, scientists have been puzzled for decades about how the process ...
Cell & Microbiology
Feb 22, 2018
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242
Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. This new invention can greatly contribute to more effective and selective ...
Bio & Medicine
Feb 8, 2019
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369
Nanopores are ideally suited for threading DNA molecules through them, enabling the genetic code to be read out. Researchers from TU Delft want to make this technology even more powerful by equipping the pores with 'plasmonics'. ...
Bio & Medicine
Sep 12, 2013
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Molecules that accumulate at the tip of chromosomes are known to play a key role in preventing damage to our DNA. Now, researchers at EPFL have unraveled how these molecules home in on specific sections of chromosomes—a ...
Cell & Microbiology
Oct 14, 2020
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252
Like a pea going through a straw, tiny molecules can pass through microscopic cylinders known as nanotubes. This could potentially be used to select molecules according to size—for example, to purify water by allowing water ...
Nanophysics
Sep 12, 2013
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(PhysOrg.com) -- Two Cornell professors will combine their inventions to develop a handheld pathogen detector that will give health care workers in the developing world speedy results to identify in the field such pathogens ...
Biochemistry
Jan 31, 2012
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The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...
Molecular & Computational biology
Oct 17, 2019
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76
As efforts such as The Cancer Genome Atlas and others generate vast quantities of information about the genetic makeup of different types of cancer, it is becoming increasingly clear that such information has great potential ...
Bio & Medicine
Feb 19, 2010
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