First bacterial genome created entirely with a computer

All the genome sequences of organisms known throughout the world are stored in a database belonging to the National Center for Biotechnology Information in the United States. As of today, the database has an additional entry: ...

A fail-safe mechanism for DNA repair

Single-molecule fluorescent measurements provide fresh insights into a process for keeping errors out of our genomes.

Biologists develop new method of cloning

DNA, which contains the genetic information of an organism, consists of long chains of nucleotides. In order to study the functions based on the sequence of these building blocks, DNA molecules must be inserted in carrier ...

Directed evolution builds nanoparticles

The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...

Nanomachines taught to fight cancer

Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. This new invention can greatly contribute to more effective and selective ...

How transcription factors explore the genome

Transcription factors (TFs) are proteins that regulate the transcription of genes, which is the first step in making a protein. The way TFs work is by searching the entire genome and binding to specific regions that regulate ...

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