A team of genetic engineers at the Salk Institute for Biological Studies, working with a colleague from Universidad Católica San Antonio de Murcia, has demonstrated transgenerational epigenetic inheritance in a methylation-edited ...
If one imagines the genome as an instruction manual for the functioning of a cell, every page of this manual is covered with annotations, highlights, and bookmarks. The role of some of these marks remains mysterious—do ...
Cell & Microbiology
Feb 20, 2023
0
110
Our genes are encoded in the DNA sequence of the genome, which is highly similar across the diverse cell types of our body. Yet, each cell can only access those genes that are in an epigenetically permissive state. The epigenome ...
Evolution
Jan 18, 2023
2
84
The co-option between viruses and humans plays important roles during human evolution. Endogenous retroviruses (ERVs), belonging to long terminal repeat retrotransposons, are a relic of ancient retroviral infection, fixed ...
Cell & Microbiology
Jan 16, 2023
0
107
A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology. Researchers developed a highly sensitive, quantitative mass spectrometry-based approach, called ...
Cell & Microbiology
Jan 12, 2023
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65
As seasoned gardeners know, broccoli heads don't develop properly and can resemble cauliflower when grown in higher temperatures.
Molecular & Computational biology
Jan 9, 2023
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23
Anyone who's ever had a dog knows how different one can be from another. For example, they can be reserved or friendly, playful or calm, fearful or bold, and prone to bark or fetch or not. Research has shown that some of ...
Molecular & Computational biology
Dec 15, 2022
1
424
DNA methylation is a biological process through which methyl groups are added to the DNA (genetic material). It is used as an epigenetic, i.e., a non-genetic strategy by prokaryotes to perform an array of functions such as ...
Cell & Microbiology
Dec 7, 2022
0
10
Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...
Cell & Microbiology
Dec 6, 2022
0
6
LMU molecular biologist Gunnar Schotta has investigated which mechanisms prevent endogenous retroviruses from becoming overly active.
Molecular & Computational biology
Sep 19, 2022
0
4
