Related topics: cancer cells · cells · dna repair · breast cancer · cancer

To repair DNA damage, plants need good contractors

When a building is damaged, a general contractor often oversees various subcontractors—framers, electricians, plumbers and drywall hangers—to ensure repairs are done in the correct order and on time.

How invading jumping genes are thwarted

Since Carnegie Institution's Barbara McClintock received her Nobel Prize on her discovery of jumping genes in 1983, we have learned that almost half of our DNA is made up of jumping genes—called transposons. Given their ...

Biologists discover source for boosting tumor cell drug sensitivity

DNA-damaging agents, or "DDAs," make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance—either present in cancer cells from the disease onset or arising during ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

Mayo researchers find off/on switch for DNA repair protein

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...

Timing is key for bacteria surviving antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth ...

How does plant DNA avoid the ravages of UV radiation?

If the ultraviolet radiation from the sun damages human DNA to cause health problems, does UV radiation also damage plant DNA? The answer is yes, but because plants can't come in from the sun or slather on sunblock, they ...

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