Fishing for proteins: Scientists use new optical tweezer technology to study DNA repair
Tucked away in a small, dark room at UPMC Hillman Cancer Center, Brittani Schnable is on a fishing expedition.
Tucked away in a small, dark room at UPMC Hillman Cancer Center, Brittani Schnable is on a fishing expedition.
Biotechnology
Mar 1, 2023
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88
People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene (BaP), is known to damage ...
Molecular & Computational biology
Feb 22, 2023
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19
The skin is presumably the largest and one of the most versatile body organs. By providing a physical barrier, it protects our body from environmental assaults. Melanin—a natural pigment produced by specialized skin cells ...
Cell & Microbiology
Jan 10, 2023
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86
A recent study by Prof. Chong Kang's group from the Institute of Botany of the Chinese Academy of Sciences (CAS) has revealed a novel cold domesticated repair mechanism for DNA damage in rice, providing corresponding elite ...
Molecular & Computational biology
Jan 6, 2023
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159
Whether radiation exposure of fathers can have consequences on their children is one of the most long-standing questions in radiation biology. Using the nematode Caenorhabditis elegans as a model, Professor Dr. Björn Schumacher ...
Molecular & Computational biology
Dec 21, 2022
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33
A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus—a finding ...
Cell & Microbiology
Sep 2, 2022
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163
DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential ...
Molecular & Computational biology
Aug 11, 2022
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240
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
Biotechnology
Aug 9, 2022
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3005
A team of researchers from Portugal, Israel, Poland and Spain has found the gene that prompts the parasite Trypanosoma brucei to change from its normal long, slender shape to one that is short and stumpy. In their paper published ...
Researchers from the Microbeam Technology and Applications Group at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) have discovered the high turnover and rescue effect of an important scaffold ...
Molecular & Computational biology
May 20, 2022
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