News tagged with dna damage

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Repairing DNA lesions

Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ...

dateJun 25, 2014 in Biochemistry
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New functions for chromatin remodelers

Large molecular motors consisting of up to a dozen different proteins regulate access to the genome, which is essential for the transcription of genes and for the repair of DNA damage. Susan Gasser and her ...

dateAug 28, 2014 in Cell & Microbiology
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A novel DNA damage alarm

How does our body keep its DNA intact? Researchers at Erasmus MC have just found a new piece of this puzzle. They discovered a novel alarm that cells use to signal DNA damage. "We already knew that DNA damage triggers an ...

dateJun 25, 2015 in Cell & Microbiology
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