Related topics: cancer cells · cells · dna repair · breast cancer · cancer

A bacterial toxin that acts as a mediator rather than a killer

Traditionally, bacterial toxins have been seen as killers of target cells. But is there more than meets the eye? Umeå University Professor Teresa Frisan and her team have discovered that toxin-host interactions are more ...

One enzyme dictates cells' response to a probable carcinogen: study

In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, ...

New findings shed light on the repair of UV-induced DNA damage

An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light. The investigators at Kobe University ...

Histone degradation after DNA damage enhances repair

DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...

RNA information transfer could be used in repairing DNA

Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...

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