Related topics: cancer cells · cells · dna repair · breast cancer · cancer

YEATS protein potential therapeutic target for cancer

Federal Express and UPS are no match for the human body when it comes to distribution. There exists in cancer biology an impressive packaging and delivery system that influences whether your body will develop cancer or not.

How to remove tangles in your DNA

(Phys.org) —DNA damage is a fact of life. On any given day, an organism's DNA will suffer between 10,000 and 1,000,000 breaks or other damage. These problems are repaired by enzymes in our cells that fix the breaks, remove ...

Ancient protein-making enzyme moonlights as DNA protector

Scientists at The Scripps Research Institute (TSRI) have found that an enzyme best known for its fundamental role in building proteins has a second major function: to protect DNA during times of cellular stress.

Cellular RNA can template DNA repair in yeast

The ability to accurately repair DNA damaged by spontaneous errors, oxidation or mutagens is crucial to the survival of cells. This repair is normally accomplished by using an identical or homologous intact sequence of DNA, ...

New functions for chromatin remodelers

Large molecular motors consisting of up to a dozen different proteins regulate access to the genome, which is essential for the transcription of genes and for the repair of DNA damage. Susan Gasser and her team now reveal ...

Reconstructing the life history of a single cell

Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build ...

Repairing DNA lesions

Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ζ (Polζ) is ...

Chernobyl's birds are adapting to ionising radiation

Birds in the exclusion zone around Chernobyl are adapting to – and may even be benefiting from – long-term exposure to radiation, ecologists have found. The study, published in the British Ecological Society's journal ...

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