Researchers uncover human DNA repair by nuclear metamorphosis

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

First images of an 'upgraded' CRISPR tool

Columbia scientists have captured the first images of a new gene editing tool that could improve upon existing CRISPR-based tools. The team developed the tool, called INTEGRATE, after discovering a unique "jumping gene" in ...

DNA breaks in nerve cells' ancestors cluster in specific genes

The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston ...

Breaking up is hard to do (especially for sex chromosomes)

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the instructions for initiating ...

Researchers reveal DNA repair mechanism

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

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