Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED. TALEDs are base editors ...
Biotechnology
Apr 25, 2022
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44
By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them. Researchers from the University ...
Molecular & Computational biology
Mar 1, 2022
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251
Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the Perelman School of Medicine at the University of Pennsylvania. ...
Biochemistry
Oct 28, 2021
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674
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every ...
Molecular & Computational biology
Sep 28, 2021
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527
DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing ...
Molecular & Computational biology
Sep 13, 2021
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466
New research from the Okinawa Institute of Science and Technology Graduate University (OIST) and Tokyo University of Marine Science and Technology has resulted in a useful genetic resource on the kuruma shrimp. These are ...
Plants & Animals
Sep 13, 2021
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17
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization ...
Cell & Microbiology
Apr 15, 2021
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59
DNA nanotechnology—the research field using DNA molecules as building material—has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures. DNA nanostructures, such as ...
Bio & Medicine
Mar 1, 2021
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14
The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target. Though CRISPR has completely changed the pace of ...
Biotechnology
Feb 23, 2021
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7
DNA molecules express heredity through genetic information. However, in the past few years, scientists have discovered that DNA can conduct electrical currents. This makes it an interesting candidate for roles that nature ...
Nanomaterials
Sep 16, 2020
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119
