Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...
Biotechnology
Jul 30, 2020
0
425
Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without causing double-stranded DNA breaks, hold great promise for gene therapy in human disease and trait improvement in crop ...
Biotechnology
Jul 27, 2020
0
5
New genome-editing technologies developed by researchers in J. Keith Joung's laboratory at the Massachusetts General Hospital (MGH) have the potential to help understand disease-associated genetic mutations that are based ...
Cell & Microbiology
Jul 23, 2020
0
345
A team of researchers at the Chinese Academy of Sciences has found that two varieties of red panda actually comprise two different species. In their paper published in the journal Science Advances, the group describes the ...
CRISPR-based gene editing has potential therapeutic benefits but also some technical shortcomings. One set of these gene editing tools, base editors, can rewrite the four individual DNA letters, or bases— A, C, T or G—which ...
Biotechnology
Feb 11, 2020
0
26
How did the monstrous giant squid—reaching school-bus size, with eyes as big as dinner plates and tentacles that can snatch prey 10 yards away—get so scarily big?
Biotechnology
Jan 16, 2020
0
2197
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology—CRISPR-Cas9 and a reverse transcriptase—into a ...
Biotechnology
Oct 21, 2019
2
339
Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells.
Biotechnology
Aug 22, 2019
0
317
Scientists in Japan have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, their method ...
Biochemistry
Jun 14, 2019
0
7
In a study published in Nature on June 10, researchers from Dr. Yang Hui's Lab at the Institute of Neuroscience of the Chinese Academy of Sciences (CAS), and collaborators from the CAS-MPG Partner Institute for Computational ...
Biotechnology
Jun 10, 2019
2
147
