News tagged with differential splicing
Getting more from whole-transcript microarrays
The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...
May 21, 2009 |
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Molecular ticket determines RNA's destination and speed inside egg cell
Like any law-abiding train passenger, a molecule called oskar RNA carries a stamped ticket detailing its destination and form of transport, scientists at the European Molecular Biology Laboratory (EMBL) in ...
Mar 18, 2012 |
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Researchers discover a switch that controls stem cell pluripotency
Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single ...
Sep 15, 2011 |
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Aging, interrupted (w/ Video)
The current pace of population aging is without parallel in human history but surprisingly little is known about the human aging process, because lifespans of eight decades or more make it difficult to study. ...
Medicine & Health / Medical research
Feb 23, 2011 |
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UW-Madison Researchers Find New Subtype of Breast Cancer
(PhysOrg.com) -- An alteration in a gene not normally associated with breast cancer has been found in up to 20 percent of breast cancer tumors and may help predict which breast cancers are more likely to turn aggressive and ...
Jun 11, 2010 |
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Scientists identify wide variety of genetic splicing in embryonic stem cells
Like homing in to an elusive radio frequency in a busy city, human embryonic stem cells must sort through a seemingly endless number of options to settle on the specific genetic message, or station, that instructs them to ...
Mar 01, 2010 |
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Scientists map epigenome of human stem cells during development
Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development.
Feb 03, 2010 |
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DNA needs a good editor: Researchers unravel the mysteries of DNA packaging
Imagine a huge spool of film containing thousands of sequences of random scenes. Without a talented editor, a screening would have no meaning.
Dec 14, 2009 |
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Human genes sing different tunes in different tissues
Scientists have long known that it's possible for one gene to produce slightly different forms of the same protein by skipping or including certain sequences from the messenger RNA. Now, an MIT team has shown that this phenomenon, ...
Biology /
Nov 02, 2008 |
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RNA interference plays bigger role than previously thought
In a paper published today online in the journal Nature, IBM and the Genome Institute of Singapore (GIS) reported findings from a joint research study that provides new information on how stem cell differentiation is con ...
Biology /
Sep 17, 2008 |
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Evolution with a restricted number of genes
The development of higher forms of life would appear to have been influenced by RNA polymerase II. This enzyme transcribes the information coded by genes from DNA into messenger-RNA (mRNA), which in turn is the basis for ...
Biology /
Dec 14, 2007 |
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List of search results for differential splicing
