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Efficient preparation of a set of potential glycosidase inhibitors

(Phys.org) -- In many biological and pathological processes, glycosidase enzymes attack glycosidic bonds in carbohydrates, glycoproteins, and glycolipids. The ability to modify or block these processes by ...

Chemistry / Biochemistry

created May 29, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New, inexpensive paper-based diabetes test ideal for developing countries

With epidemics of Type 2 diabetes looming in rural India, China and other areas of the world where poverty limits the availability of health care, scientists are reporting development of an inexpensive and ...

Chemistry / Analytical Chemistry

created May 16, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Licorice root found to contain anti-diabetic substance

It provides the raw material for liquorice candy, calms the stomach and alleviates diseases of the airways: liquorice root. Chosen as the "Medicinal plant 2012", the root has been treasured in traditional healing since ancient ...

Chemistry / Biochemistry

created Apr 17, 2012 | popularity 5 / 5 (2) | comments 0

Blood on the menu: New research could make it easier to grow health-promoting blood oranges

For the red pigmentation to develop, blood oranges normally require a period of cold as they ripen. The only place to reliably grow them on a commercial scale is in the Sicilian area of Italy around Mount ...

Biology / Biotechnology

created Mar 13, 2012 | popularity 5 / 5 (1) | comments 1

Insulin, nutrition prevent blood stem cell differentiation in fruit flies

UCLA stem cell researchers have shown that insulin and nutrition keep blood stem cells from differentiating into mature blood cells in Drosophila, the common fruit fly, a finding that has implications for studying inflammatory ...

Biology / Cell & Microbiology

created Mar 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers develop paper-thin device to test cholesterol levels

(PhysOrg.com) -- Paper-thin sensors that use the latest technology in miniaturization and printing could revolutionize the way point of care testing is carried out for cholesterol and lead to further applications ...

Chemistry / Analytical Chemistry

created Feb 29, 2012 | popularity 3 / 5 (1) | comments 2

Diabetes mellitus

Diabetes mellitus (pronounced /ˌdaɪ.əˈbiːtiːz/ or /ˌdaɪ.əˈbiːtɨs/; /mɨˈlaɪtəs/ or /ˈmɛlɨtəs/)—often referred to simply as diabetes—is a disease in which the body does not produce enough, or properly respond to, insulin, a hormone produced in the pancreas. Insulin is needed to turn sugar and other food into energy. In diabetes, the body either doesn't make enough insulin or can't use its own insulin as well as it should, or both. This causes sugar to accumulate in the blood, often leading to various complications. The American Diabetes Association reported in 2009 that there are 23.6 million children and adults in the United States—7.8% of the population, who have diabetes. While an estimated 17.9 million in the US alone have been diagnosed with diabetes, nearly one in four (5.7 million) diabetics are unaware that they have the disease.

Many types of diabetes are recognized: The principal three are:

All forms of diabetes have been treatable since insulin became medically available in 1921, but there is no cure for the common types except a pancreas transplant, although gestational diabetes usually resolves after delivery. Diabetes and its treatments can cause many complications. Acute complications including hypoglycemia, diabetic ketoacidosis, or nonketotic hyperosmolar coma may occur if the disease is not adequately controlled. Serious long-term complications include cardiovascular disease, chronic renal failure, retinal damage, which can lead to blindness, several types of nerve damage, and microvascular damage, which may cause erectile dysfunction and poor wound healing. Poor healing of wounds, particularly of the feet, can lead to gangrene, and possibly to amputation. Adequate treatment of diabetes, as well as increased emphasis on blood pressure control and lifestyle factors such as not smoking and maintaining a healthy body weight, may improve the risk profile of most of the chronic complications. In the developed world, diabetes is the most significant cause of adult blindness in the non-elderly and the leading cause of non-traumatic amputation in adults, and diabetic nephropathy is the main illness requiring renal dialysis in the United States.

For more information about Diabetes mellitus, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.