News tagged with dendritic cells

New fluorescent biosensor reveals mechanism critical to immune system amplification

Using a new fluorescent biosensor they developed, researchers at Carnegie Mellon University have discovered how a key set of immune cells exchange information during their coordinated assault on invading pathogens. The immune ...

Chemistry / Biochemistry

created Apr 23, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Researchers identify signals triggering dendrite growth

A study in worms that are less than a millimetre long has yielded clues that may be important for understanding how nerves grow.

Biology / Other

created Sep 20, 2011 | popularity 5 / 5 (1) | comments 0

Researchers publish study on neuronal RNA targeting

SUNY Downstate scientist Ilham Muslimov, MD, PhD, along with senior author Henri Tiedge, PhD, professor of physiology and pharmacology and of neurology, published a study suggesting that cellular dysregulation associated ...

Biology / Cell & Microbiology

created Sep 07, 2011 | popularity 5 / 5 (1) | comments 0

'I'm a tumor and I'm over here!' Nanovaults used to prod immune system to fight cancer (w/ video)

(PhysOrg.com) -- UCLA scientists have discovered a way to wake up the immune system to fight cancer by delivering an immune system-stimulating protein in a nanoscale container called a vault directly into ...

Nanotechnology / Bio & Medicine

created May 03, 2011 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Personlized dendritic cell vaccine increases survival in patients with deadly brain cancer

A dendritic cell vaccine personalized for each individual based on the patient's own tumor may increase median survival time in those with a deadly form of brain cancer called glioblastoma, an early phase study at UCLA's ...

Medicine & Health / Cancer

created Mar 17, 2011 | popularity 5 / 5 (1) | comments 0

New microscope decodes complex eye circuitry (w/ Video)

The sensory cells in the retina of the mammalian eye convert light stimuli into electrical signals and transmit them via downstream interneurons to the retinal ganglion cells which, in turn, forward them to ...

Medicine & Health / Medical research

created Mar 09, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Rewrite the textbooks: Findings challenge conventional wisdom of how neurons operate

(PhysOrg.com) -- Neurons are complicated, but the basic functional concept is that synapses transmit electrical signals to the dendrites and cell body (input), and axons carry signals away (output). In one ...

Medicine & Health / Neuroscience

created Feb 17, 2011 | popularity 4.9 / 5 (51) | comments 15 | with audio podcast

Study uses the patient's tumor to form vaccine

A new process for creating a personalized vaccine may become a crucial tool in helping patients with colorectal cancer develop an immune response against their own tumors. This dendritic cell (DC) vaccine, developed at Dartmouth ...

Medicine & Health / Cancer

created Nov 24, 2010 | popularity 5 / 5 (1) | comments 0

New class of 'dancing' dendritic cells derived from blood monocytes

Dendritic cells, known to be the prime movers of the body's immune response, are still notoriously difficult to study in humans. Samples, which come primarily from bone marrow or lymphoid tissue, are simply too difficult ...

Biology / Cell & Microbiology

created Nov 10, 2010 | popularity not rated yet | comments 0

Researchers turn off severe food allergies in mice

Johns Hopkins scientists have discovered a way to turn off the immune system's allergic reaction to certain food proteins in mice, a discovery that could have implications for the millions of people who suffer severe reactions ...

Medicine & Health / Medical research

created Oct 02, 2010 | popularity 5 / 5 (8) | comments 3 | with audio podcast

Novel sensing mechanism discovered in dendritic cells to increase immune response to HIV

Dendritic cells are the grand sentinels of the immune system, standing guard 24/7 to detect foreign invaders such as viruses and bacteria, and bring news of the invasion to other immune cells to marshal an ...

Medicine & Health / HIV & AIDS

created Sep 08, 2010 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Dendritic cells found in zebrafish

(PhysOrg.com) -- Scientists from the University of California, San Diego School of Medicine have identified dendritic antigen-presenting cells in zebrafish, opening the possibility that the tiny fish could become a new model ...

Biology / Cell & Microbiology

created Sep 08, 2010 | popularity not rated yet | comments 0 | with audio podcast

New HIV vaccine trial first to target dendritic cells

When HIV was first discovered to cause AIDS in 1981, prominent scientists expected to have an effective vaccine within a couple of years. Three decades later, the disease has killed more than 25 million people and defied ...

Medicine & Health / HIV & AIDS

created Jul 05, 2010 | popularity not rated yet | comments 0

A cell turns into a virus factory

Bunyaviruses are poorly researched, despite their diversity and importance in relation to animal and human diseases. ETH Zurich researchers led by virologist Ari Helenius have now discovered the tricks used ...

Biology / Cell & Microbiology

created Jun 25, 2010 | popularity 4.5 / 5 (4) | comments 1

Rare hybrid cell key to regulating the immune system

A cell small in number but powerful in its ability to switch the immune system on or off is a unique hybrid of two well-known immune cell types, Medical College of Georgia researchers report.

Medicine & Health / Medical research

created May 24, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Dendritic cell

Dendritic cells (DCs) are immune cells that form part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells.

Dendritic cells are present in small quantities in tissues that are in contact with the external environment, mainly the skin (where there is a specialized dendritic cell type called Langerhans cells) and the inner lining of the nose, lungs, stomach and intestines. They can also be found in an immature state in the blood. Once activated, they migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and shape the adaptive immune response. At certain development stages they grow branched projections, the dendrites, that give the cell its name. However, these do not have any special relation with neurons, which also possess similar appendages. Immature dendritic cells are also called veiled cells, in which case they possess large cytoplasmic 'veils' rather than dendrites.

For more information about Dendritic cell, read the full article at Wikipedia.
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