News tagged with cysteine protease
Scientists discover a key protein regulator of inflammation and cell death
Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.
Biology /
Jan 22, 2009 |
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Search results for cysteine protease
Biochemists discover how a ‘molecular slingshot’ disrupts key proteins
(PhysOrg.com) -- An important basic science discovery reported by University of Massachusetts Amherst biochemists this week describes how certain proteins use an unusual, spring-loaded loop mechanism to cripple their target ...
Jan 26, 2011 |
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First-ever covalent irreversible inhibition of a protease central to hepatitis C infection
Avila Therapeutics, Inc., a biotechnology company developing novel targeted covalent drugs, has published research in Nature Chemical Biology demonstrating the first-ever selective irreversible inhibition of a viral protea ...
Nov 28, 2010 |
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Cathepsin B increases apoptosis in fulminant hepatic failure
The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis. It is not known if cathepsin ...
Medicine & Health / Medical research
Mar 20, 2009 |
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Structure of a virulent pathogen revealed
(PhysOrg.com) -- Like high-profile politicians, pathogenic bacteria dispatch advance teams to make way for their arrival. But these bacterial agents don’t just secure a safe passage, as a Secret Service detail ...
Biology /
Dec 04, 2008 |
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Scientists confirm molecular clipping mechanism behind stem cell development
(PhysOrg.com) -- Stem cells don’t just become a part of the liver or the brain in a flash; it takes a complex molecular choreography and requires that specific genes be switched on and off at specific times. Some of these ...
Biology /
Nov 07, 2008 |
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Pathway to cell death redefined in landmark study
A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered ...
Medicine & Health / Medical research
Sep 20, 2007 |
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Molecular probe 'paints' cancer cells in living animals
Researchers at the Stanford University School of Medicine have developed a molecular probe that sets aglow tumor cells within living animals. Their goal is to use the probe to improve the diagnosis and treatment of cancer ...
Biology /
Sep 09, 2007 |
4.5 / 5 (20) |
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New NIST reference material for peptide analysis
The National Institute of Standards and Technology (NIST) has issued its first-ever reference material designed to improve the performance and reliability of experiments to measure the masses and concentrations of peptides ...
Biology /
May 25, 2007 |
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Enzyme shreds Alzheimer's protein
An enzyme found naturally in the brain snips apart the protein that forms the sludge called amyloid plaque that is one of the hallmarks of Alzheimer's disease (AD), researchers have found. They said their findings in mice ...
Medicine & Health / Diseases, Conditions, Syndromes
Sep 20, 2006 |
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List of search results for cysteine protease