Order from disorder in the sarcomere

Alpha-actinin can cross-link actin filaments and anchor them to the Z-disk in sarcomeres. Sarcomeres are a structural unit of myofibril in striated muscle. The FATZ (filamin, α-actinin- and telethonin-binding protein of ...

RNA: A new method to discover its high-resolution structure

The structure of a biomolecule can reveal much about its functioning and interaction with the surrounding environment. The double-helical structure of DNA and its implications for the processes of transmission of genetic ...

The molecular imaging behind COVID-19 breakthroughs

It's fair to say that before the COVID-19 pandemic, very few non-scientists could name a viral protein. But now, millions of people around the world can name the SARS-CoV-2 spike protein, and a subset of those could probably ...

Revealing the way a critical enzyme works in the cell

S-acylation is the process of chemically linking a lipid to protein via a thioester bond. It is an important process of the cell that regulates the localization and function of numerous proteins. It promotes lipid membrane ...

Atomically precise noble metal nanoclusters

Noble metal nanoparticles, such as gold and silver, are well known in the research field of catalysis and biomedical applications. For example, gold and silver nanoparticles can be good catalysts for various chemical transformations, ...

A clear path to better insights into biomolecules

An international team of scientists led by Kartik Ayyer from the MPSD has obtained some of the sharpest possible 3-D images of gold nanoparticles. The results lay the foundation for obtaining high resolution images of macromolecules. ...

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