News tagged with conformational diseases
Mechanism related to the onset of various genetic diseases revealed
Researchers at the Department of Biochemistry and Molecular Biology of Universitat Autňnoma de Barcelona (UAB) have revealed the process by which proteins with a tendency to cause conformational diseases such as amyotrophic ...
Sep 17, 2009 |
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Search results for conformational diseases
X-ray crystallography study finds way to allosterically inhibit disease-related enzyme caspase-6
Perhaps no other biochemist in the world has his own baseball card, but University of Massachusetts Amherst doctoral student Elih M. Velázquez-Delgado, who gave up a pitching career for science, does. ...
Apr 03, 2012 |
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Vitamins doing gymnastics: Scientists capture first full image of vitamin B12 in action
You see it listed on the side of your cereal box and your multivitamin bottle. It's vitamin B12, part of a nutritious diet like all those other vitamins and minerals.
Mar 27, 2012 |
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Infrared spectroscopy allows scientists to analyze protein structure on ultrafast timescale
Proteins can take many different shapes, and those shapes help determine each protein’s function. Analyzing those structures can tell scientists a great deal about how a protein behaves, but many of the ...
Chemistry / Analytical Chemistry
Mar 26, 2012 |
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Mutations in people with cancerous Lynch syndrome prevent a DNA mismatch repair protein from doing its job properly
When the cell’s DNA proofreading system encounters a mismatch in the genome, a number of repair proteins are thrown into action, ripping up the mistake and filling in the correct nucleotides. One of these ...
Mar 23, 2012 |
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Study reveals how protein machinery binds and wraps DNA to start replication
(PhysOrg.com) -- Before any cell - healthy or cancerous - can divide, it has to replicate its DNA. So scientists who want to know how normal cells work - and perhaps how to stop abnormal ones - are keen to ...
Mar 06, 2012 |
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Cholera's nano-dagger: Researchers observe how pathogen decimates competing bacteria and human cells
Bacteria live in a state of perpetual warfare, with different species battling for dominion over their competitors and when pathogen, over their infected host. New research suggests that the human pathogen Vibrio cholerae, which ...
Feb 29, 2012 |
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Researchers identify structure of key control element behind protein misfolding that can lead to disease
The gold standard for nanotechnology is nature's own proteins. These biomolecular nanomachines – macromolecules forged from peptide chains of amino acids - are able to fold themselves into a dazzling ...
Feb 24, 2012 |
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Immunoproteasome crystal structure determined
Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively ...
Feb 16, 2012 |
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Prion proteins play powerful role in survival, evolution of wild yeast strains
Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...
Feb 15, 2012 |
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High-resolution mapping of the 3D organization of chromosomes
In collaboration with researchers from the Weizmann Institute in Israel, a team from the Institut de Génétique Humaine (CNRS, France) has, for the first time, revealed the detailed three-dimensional ...
Jan 31, 2012 |
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List of search results for conformational diseases
